AutismKB 2.0

Annotation Detail for TMUB1


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Basic Information Top
Gene Symbol:TMUB1 ( C7orf21,MGC5442 )
Gene Full Name: transmembrane and ubiquitin-like domain containing 1
Band: 7q36.1
Quick LinksEntrez ID:83590; OMIM: NA; Uniprot ID:TMUB1_HUMAN; ENSEMBL ID: ENSG00000164897; HGNC ID: 21709
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult95 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor19 / 119369159
germ cell tumor17 / 26384564
glioma13 / 106883121
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma8 / 71755111
non-neoplasia4 / 9725041
normal102 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites6 / 40015149
bladder0 / 297570 
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain29 / 110098926
cervix6 / 48171124
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye12 / 21105456
heart3 / 8962633
intestine25 / 234472106
kidney8 / 21177737
larynx2 / 2414582
liver2 / 2077439
lung16 / 33697447
lymph3 / 4427067
lymph node14 / 91610152
mammary gland9 / 15327158
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary6 / 10205158
pancreas22 / 214812102
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta15 / 28082553
prostate10 / 18934552
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach4 / 9661941
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P354998
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.12 ± 0.3
Basal Forebrain6.19 ± 0.32
Basal Part of Pons6.19 ± 0.37
Cerebellar Cortex5.99 ± 0.32
Cerebellar Nuclei6.23 ± 0.28
Claustrum6.03 ± 0.5
Epithalamus5.9 ± 0.33
Frontal Lobe6.23 ± 0.39
Globus Pallidus6.14 ± 0.34
Hypothalamus6.08 ± 0.2
Insula6.08 ± 0.34
Limbic Lobe6.07 ± 0.39
Mesencephalon6.12 ± 0.37
Myelencephalon6.15 ± 0.34
Occipital Lobe5.97 ± 0.3
Parietal Lobe6.13 ± 0.32
Pontine Tegmentum5.99 ± 0.35
Striatum6.11 ± 0.29
Subthalamus5.94 ± 0.39
Temporal Lobe6.13 ± 0.32
Thalamus6.29 ± 0.25
White Matter5.95 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmub1CBCerebellum3.72
4.59
Tmub1CTXCerebral cortex1.01
1.1
Tmub1HIPHippocampal region3.61
3.73
Tmub1HPFHippocampal formation2.86
2.8
Tmub1HYHypothalamus2.49
2.94
Tmub1LSXLateral septal complex0.51
0.64
Tmub1MBMidbrain1.5
3.14
Tmub1MYMedulla4.36
6.75
Tmub1OLFOlfactory bulb12.22
11.91
Tmub1PPons4.99
8.9
Tmub1PALPallidum2.2
2.79
Tmub1RHPRetrohippocampal region1.26
1.16
Tmub1sAMYStriatum-like amygdalar nuclei2.17
2.31
Tmub1STRStriatum1.38
1.45
Tmub1STRdStriatum dorsal region0.73
0.87
Tmub1STRvStriatum ventral region3.67
3.25
Tmub1THThalamus1.13
1.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003512 31 76 106 HRGQAAQPEPSTGFTATPPAPDSPQEPLVLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018