AutismKB 2.0

Annotation Detail for C22orf13


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Basic Information Top
Gene Symbol:C22orf13 ( LLN4,MGC1842 )
Gene Full Name: chromosome 22 open reading frame 13
Band: 22q11.2
Quick LinksEntrez ID:83606; OMIM: NA; Uniprot ID:CV013_HUMAN; ENSEMBL ID: ENSG00000138867; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus30 / 56401253
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma13 / 82823156
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor39 / 263845147
glioma8 / 10688374
head and neck tumor4 / 13630229
kidney tumor6 / 6895987
leukemia12 / 95842125
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma15 / 71755209
non-neoplasia2 / 9725020
normal138 / 336030741
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor17 / 124949136
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood9 / 12347872
bone7 / 7165597
bone marrow4 / 4880181
brain39 / 110098935
cervix5 / 48171103
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine17 / 23447272
kidney18 / 21177784
larynx0 / 241450 
liver12 / 20774357
lung18 / 33697453
lymph9 / 44270203
lymph node8 / 9161087
mammary gland4 / 15327126
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary9 / 10205188
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta41 / 280825145
prostate9 / 18934547
salivary gland1 / 2015549
skin23 / 210574109
spleen4 / 5395274
stomach1 / 9661910
testis18 / 33044254
thymus9 / 81131110
thyroid0 / 474730 
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P331373
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.33 ± 1.18
Basal Forebrain2.87 ± 0.36
Basal Part of Pons2.57 ± 0.48
Cerebellar Cortex2.86 ± 0.82
Cerebellar Nuclei3.15 ± 0.71
Claustrum3.44 ± 0.96
Epithalamus2.7 ± 0.89
Frontal Lobe2.85 ± 0.92
Globus Pallidus3.52 ± 0.66
Hypothalamus2.91 ± 0.86
Insula2.52 ± 0.64
Limbic Lobe2.88 ± 0.82
Mesencephalon3.15 ± 0.88
Myelencephalon2.91 ± 0.76
Occipital Lobe3.15 ± 0.87
Parietal Lobe2.98 ± 0.86
Pontine Tegmentum3.02 ± 0.94
Striatum3.24 ± 0.89
Subthalamus3.31 ± 0.71
Temporal Lobe2.75 ± 0.77
Thalamus2.82 ± 0.79
White Matter3.71 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018