AutismKB 2.0

Annotation Detail for ZMIZ2


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Basic Information Top
Gene Symbol:ZMIZ2 ( DKFZp761I2123,KIAA1886,NET27,TRAFIP20,ZIMP7,hZIMP7 )
Gene Full Name: zinc finger, MIZ-type containing 2
Band: 7p13
Quick LinksEntrez ID:83637; OMIM: 611196; Uniprot ID:ZMIZ2_HUMAN; ENSEMBL ID: ENSG00000122515; HGNC ID: 22229
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst2 / 6231932
fetus23 / 56401240
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult112 / 193912157
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor4 / 34366116
chondrosarcoma5 / 8282360
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor10 / 26384537
glioma16 / 106883149
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal166 / 336030749
ovarian tumor3 / 7668239
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal21 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites7 / 40015174
bladder0 / 297570 
blood5 / 12347840
bone4 / 7165555
bone marrow1 / 4880120
brain88 / 110098979
cervix5 / 48171103
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine17 / 23447272
kidney9 / 21177742
larynx1 / 2414541
liver3 / 20774314
lung27 / 33697480
lymph0 / 442700 
lymph node4 / 9161043
mammary gland6 / 15327139
mouth1 / 6705214
muscle1 / 1077159
nerve4 / 15768253
ovary4 / 10205139
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate11 / 18934558
salivary gland0 / 201550 
skin10 / 21057447
spleen6 / 53952111
stomach3 / 9661931
testis9 / 33044227
thymus12 / 81131147
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver3 / 20774314
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 54970_at
Cell line Expression level Expression bar
721_B_lymphoblasts229.25
Adipocyte25.1
AdrenalCortex80.15
Adrenalgland63.45
Amygdala137.75
Appendix67.6
AtrioventricularNode41.45
BDCA4+_DentriticCells330.4
Bonemarrow86.35
BronchialEpithelialCells29
CD105+_Endothelial77.55
CD14+_Monocytes101.35
CD19+_BCells(neg._sel.)297.85
CD33+_Myeloid196.5
CD34+197.15
CD4+_Tcells254.9
CD56+_NKCells163.05
CD71+_EarlyErythroid93.55
CD8+_Tcells193.3
CardiacMyocytes42.8
Caudatenucleus76.9
Cerebellum63.95
CerebellumPeduncles80.75
CiliaryGanglion33.3
CingulateCortex157.1
Colorectaladenocarcinoma171.85
DorsalRootGanglion60.9
FetalThyroid154.45
Fetalbrain259
Fetalliver44.7
Fetallung55.9
GlobusPallidus74.3
Heart139.65
Hypothalamus167.75
Kidney49.45
Leukemia_chronicMyelogenousK-56240.65
Leukemia_promyelocytic-HL-60130.05
Leukemialymphoblastic(MOLT-4)47.75
Liver107.4
Lung191.95
Lymphnode126.3
Lymphoma_burkitts(Daudi)82.95
Lymphoma_burkitts(Raji)387.15
MedullaOblongata127.4
OccipitalLobe81.75
OlfactoryBulb61.7
Ovary25.15
Pancreas72.65
PancreaticIslet113.95
ParietalLobe83.75
Pituitary69.8
Placenta57.7
Pons74
PrefrontalCortex404.25
Prostate146.35
Salivarygland55.15
SkeletalMuscle29.35
Skin63.5
SmoothMuscle55.1
Spinalcord109.9
SubthalamicNucleus115.1
SuperiorCervicalGanglion75.05
TemporalLobe155.25
Testis88.7
TestisGermCell58
TestisIntersitial63.5
TestisLeydigCell66.55
TestisSeminiferousTubule59.75
Thalamus88.55
Thymus87.5
Thyroid125.65
Tongue60.25
Tonsil83.5
Trachea60.3
TrigeminalGanglion49.95
Uterus55.9
UterusCorpus54.4
WholeBlood73.8
Wholebrain204.65
colon51.7
pineal_day91.16
pineal_night68.4
retina105.9
small_intestine48.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P315066
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.56 ± 0.52
Basal Forebrain6.13 ± 0.27
Basal Part of Pons6.13 ± 0.37
Cerebellar Cortex5.71 ± 0.3
Cerebellar Nuclei6.21 ± 0.31
Claustrum6.79 ± 0.52
Epithalamus5.42 ± 0.28
Frontal Lobe6.01 ± 0.4
Globus Pallidus6.27 ± 0.34
Hypothalamus5.58 ± 0.54
Insula6.12 ± 0.27
Limbic Lobe6.2 ± 0.37
Mesencephalon6.04 ± 0.37
Myelencephalon6.09 ± 0.42
Occipital Lobe6.1 ± 0.43
Parietal Lobe6.14 ± 0.47
Pontine Tegmentum5.92 ± 0.5
Striatum6.27 ± 0.4
Subthalamus5.97 ± 0.02
Temporal Lobe6.1 ± 0.36
Thalamus5.91 ± 0.34
White Matter6.35 ± 0.5
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018