Annotation Detail for SESN2
Basic Information Top
| Gene Symbol: | SESN2 ( DKFZp761M0212,DKFZp761M02121,HI95,SES2,SEST2 ) |
|---|---|
| Gene Full Name: | sestrin 2 |
| Band: | 1p35.3 |
| Quick Links | Entrez ID:83667; OMIM: 607767; Uniprot ID:SESN2_HUMAN; ENSEMBL ID: ENSG00000130766; HGNC ID: 20746 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.469543
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 10 / 70761 | 141 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 68 / 1939121 | 35 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 126 / 3360307 | 37 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 14 / 104616 | 133 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 1 / 102680 | 9 |  |
| retinoblastoma | 16 / 46356 | 345 |  |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 15 / 125191 | 119 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 12 / 1100989 | 10 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 19 / 211054 | 90 | |
| heart | 2 / 89626 | 22 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 12 / 336974 | 35 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 8 / 107715 | 74 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 19 / 214812 | 88 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 22 / 280825 | 78 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 9 / 210574 | 42 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 5 / 330442 | 15 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_673_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.26 ± 0.76 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.61 ± 0.55 | |
| Basal Part of Pons | 3.11 ± 0.69 | |
| Cerebellar Cortex | 2.96 ± 0.68 | |
| Cerebellar Nuclei | 3.09 ± 0.72 | |
| Claustrum | 3.51 ± 0.96 | |
| Epithalamus | 2.59 ± 0.82 | |
| Frontal Lobe | 2.97 ± 0.64 | |
| Globus Pallidus | 2.73 ± 0.78 | |
| Hypothalamus | 2.86 ± 0.41 | |
| Insula | 2.69 ± 0.97 | |
| Limbic Lobe | 2.92 ± 0.54 | |
| Mesencephalon | 3.07 ± 0.64 | |
| Myelencephalon | 3.02 ± 0.66 | |
| Occipital Lobe | 3 ± 0.62 | |
| Parietal Lobe | 3.04 ± 0.6 | |
| Pontine Tegmentum | 2.93 ± 0.71 | |
| Striatum | 2.64 ± 0.69 | |
| Subthalamus | 3.16 ± 0.41 | |
| Temporal Lobe | 2.97 ± 0.63 | |
| Thalamus | 2.99 ± 0.66 | |
| White Matter | 2.47 ± 0.45 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sesn2 | CB | Cerebellum | 0.76 | |
| 1.17 | | |||
| Sesn2 | CTX | Cerebral cortex | 4.29 | |
| 3.48 | | |||
| Sesn2 | HIP | Hippocampal region | 1.92 | |
| 2.4 | | |||
| Sesn2 | HPF | Hippocampal formation | 1.53 | |
| 1.71 | | |||
| Sesn2 | HY | Hypothalamus | 0.17 | |
| 0.29 | | |||
| Sesn2 | LSX | Lateral septal complex | 0.05 | |
| 0 | | |||
| Sesn2 | MB | Midbrain | 0.71 | |
| 1.21 | | |||
| Sesn2 | MY | Medulla | 0.69 | |
| 1.37 | | |||
| Sesn2 | OLF | Olfactory bulb | 1.59 | |
| 1.95 | | |||
| Sesn2 | P | Pons | 0.4 | |
| 0.68 | | |||
| Sesn2 | PAL | Pallidum | 0.12 | |
| 0.17 | | |||
| Sesn2 | RHP | Retrohippocampal region | 0.69 | |
| 0.58 | | |||
| Sesn2 | sAMY | Striatum-like amygdalar nuclei | 0.23 | |
| 0.71 | | |||
| Sesn2 | STR | Striatum | 0.25 | |
| 0.45 | | |||
| Sesn2 | STRd | Striatum dorsal region | 0.28 | |
| 0.37 | | |||
| Sesn2 | STRv | Striatum ventral region | 0.22 | |
| 0.67 | | |||
| Sesn2 | TH | Thalamus | 1.16 | |
| 2.39 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| SESN2_HUMAN_1 | 9 | 1 | 9 | MIVADSECR | PRIDE |
| SESN2_HUMAN_264 | 22 | 264 | 285 | MQQLQESLLRDEGTSQEEMESR | PRIDE |