AutismKB 2.0

Annotation Detail for HIST1H4E


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Basic Information Top
Gene Symbol:HIST1H4E ( H4/j,H4FJ,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4F,HIST1H4H,HIST1H4I,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4A,HIST2H4B,HIST4H4 )
Gene Full Name: histone cluster 1, H4e
Band: 6p22.2
Quick LinksEntrez ID:8367; OMIM: 602830; Uniprot ID:H4_HUMAN; ENSEMBL ID: ENSG00000198518; HGNC ID: 4790
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal10 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214634_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.7
Adipocyte20.2
AdrenalCortex22.45
Adrenalgland20.3
Amygdala17.4
Appendix29.3
AtrioventricularNode19.7
BDCA4+_DentriticCells21.1
Bonemarrow24.8
BronchialEpithelialCells18.9
CD105+_Endothelial20.1
CD14+_Monocytes21.9
CD19+_BCells(neg._sel.)20.45
CD33+_Myeloid25.4
CD34+19.55
CD4+_Tcells20.85
CD56+_NKCells18.45
CD71+_EarlyErythroid20.7
CD8+_Tcells16.15
CardiacMyocytes20.8
Caudatenucleus18.25
Cerebellum17.55
CerebellumPeduncles37.7
CiliaryGanglion20.45
CingulateCortex26.25
Colorectaladenocarcinoma20.45
DorsalRootGanglion25.6
FetalThyroid24.6
Fetalbrain20.8
Fetalliver21.4
Fetallung19.65
GlobusPallidus15.65
Heart25.85
Hypothalamus22.4
Kidney18
Leukemia_chronicMyelogenousK-56218.45
Leukemia_promyelocytic-HL-6017.95
Leukemialymphoblastic(MOLT-4)21.5
Liver27.35
Lung21.6
Lymphnode20.45
Lymphoma_burkitts(Daudi)26
Lymphoma_burkitts(Raji)27.85
MedullaOblongata19.9
OccipitalLobe22.85
OlfactoryBulb17.9
Ovary25.5
Pancreas18.65
PancreaticIslet21.65
ParietalLobe27.65
Pituitary25.25
Placenta19.9
Pons31.7
PrefrontalCortex24.7
Prostate22.7
Salivarygland16.4
SkeletalMuscle37.3
Skin24.85
SmoothMuscle21.05
Spinalcord21.9
SubthalamicNucleus21.1
SuperiorCervicalGanglion22.9
TemporalLobe23.25
Testis17.45
TestisGermCell18.35
TestisIntersitial19.65
TestisLeydigCell26
TestisSeminiferousTubule23
Thalamus25.95
Thymus15.3
Thyroid22.1
Tongue20.65
Tonsil31.8
Trachea17.6
TrigeminalGanglion34.5
Uterus15.6
UterusCorpus21.7
WholeBlood22.35
Wholebrain12.1
colon19.45
pineal_day20.66
pineal_night18.34
retina25.675
small_intestine13.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_522_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.02 ± 0.25
Basal Forebrain12.77 ± 0.41
Basal Part of Pons12.32 ± 0.3
Cerebellar Cortex13.08 ± 0.37
Cerebellar Nuclei12.54 ± 0.31
Claustrum12.9 ± 0.26
Epithalamus12.46 ± 0.7
Frontal Lobe12.71 ± 0.43
Globus Pallidus11.9 ± 0.38
Hypothalamus13.16 ± 0.32
Insula12.8 ± 0.39
Limbic Lobe12.65 ± 0.36
Mesencephalon12.66 ± 0.39
Myelencephalon12.65 ± 0.38
Occipital Lobe12.67 ± 0.3
Parietal Lobe12.89 ± 0.39
Pontine Tegmentum12.87 ± 0.41
Striatum12.26 ± 0.39
Subthalamus12.66 ± 0.26
Temporal Lobe12.8 ± 0.32
Thalamus12.47 ± 0.37
White Matter11.93 ± 0.19
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
H4_HUMAN_0 0 0 0 DNIQGITKPAIR PRIDE
H4_HUMAN_0 0 0 0 TVTAMDVVYALK PRIDE
H4_HUMAN_0 0 0 0 TVTAMDVVYALKR PRIDE
H4_HUMAN_0 0 0 0 VFLENVIR PRIDE
H4_HUMAN_23 13 23 35 RDNIQGITKPAIR PRIDE
H4_HUMAN_24 12 24 35 DNIQGITKPAIR PRIDE
H4_HUMAN_24 13 24 36 DNIQGITKPAIRR PRIDE
H4_HUMAN_25 11 25 35 NIQGITKPAIR PRIDE
H4_HUMAN_4 14 4 17 GKGGKGLGKGGAKR PRIDE
H4_HUMAN_45 11 45 55 RISGLIYEETR PRIDE
H4_HUMAN_46 10 46 55 ISGLIYEETR PRIDE
H4_HUMAN_46 14 46 59 ISGLIYEETRGVLK PRIDE
H4_HUMAN_5 13 5 17 KGGKGLGKGGAKR PRIDE
H4_HUMAN_56 12 56 67 GVLKVFLENVIR PRIDE
H4_HUMAN_60 18 60 77 VFLENVIRDAVTYTEHAK PRIDE
H4_HUMAN_60 8 60 67 VFLENVIR PRIDE
H4_HUMAN_68 10 68 77 DAVTYTEHAK PRIDE
H4_HUMAN_68 11 68 78 DAVTYTEHAKR PRIDE
H4_HUMAN_79 13 79 91 KTVTAMDVVYALK PRIDE
H4_HUMAN_79 14 79 92 KTVTAMDVVYALKR PRIDE
H4_HUMAN_80 12 80 91 TVTAMDVVYALK PRIDE
H4_HUMAN_80 13 80 92 TVTAMDVVYALKR PRIDE
H4_HUMAN_80 14 80 93 KTVTAMDVVYALKR PRIDE
PAp00006681 11 46 56 RISGLIYEETR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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