Annotation Detail for GRWD1
Basic Information Top
| Gene Symbol: | GRWD1 ( CDW4,GRWD,KIAA1942,RRB1,WDR28 ) |
|---|---|
| Gene Full Name: | glutamate-rich WD repeat containing 1 |
| Band: | 19q13.33 |
| Quick Links | Entrez ID:83743; OMIM: 610597; Uniprot ID:GRWD1_HUMAN; ENSEMBL ID: ENSG00000105447; HGNC ID: 21270 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.400625
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 21 / 564012 | 37 |  |
| neonate | 9 / 31097 | 289 |  |
| infant | 9 / 23620 | 381 | |
| juvenile | 17 / 55556 | 305 | |
| adult | 88 / 1939121 | 45 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 24 / 263845 | 90 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 10 / 95842 | 104 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 14 / 103127 | 135 | |
| lymphoma | 14 / 71755 | 195 | |
| non-neoplasia | 12 / 97250 | 123 | |
| normal | 247 / 3360307 | 73 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 50 / 125680 | 397 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 16 / 124949 | 128 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 2 / 29757 | 67 | |
| blood | 4 / 123478 | 32 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 113 / 1100989 | 102 | |
| cervix | 6 / 48171 | 124 | |
| connective tissue | 13 / 149255 | 87 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 12 / 211054 | 56 | |
| heart | 9 / 89626 | 100 | |
| intestine | 10 / 234472 | 42 | |
| kidney | 24 / 211777 | 113 | |
| larynx | 1 / 24145 | 41 | |
| liver | 5 / 207743 | 24 | |
| lung | 24 / 336974 | 71 | |
| lymph | 14 / 44270 | 316 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 11 / 102051 | 107 | |
| pancreas | 11 / 214812 | 51 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 14 / 280825 | 49 | |
| prostate | 14 / 189345 | 73 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 27 / 210574 | 128 | |
| spleen | 17 / 53952 | 315 | |
| stomach | 1 / 96619 | 10 | |
| testis | 7 / 330442 | 21 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 3 / 16999 | 176 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 14 / 232878 | 60 | |
| vascular | 16 / 51780 | 308 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 221549_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 67.9 | |
| Adipocyte | 48.2 | |
| AdrenalCortex | 81.95 | |
| Adrenalgland | 44.5 | |
| Amygdala | 20.25 | |
| Appendix | 44.45 | |
| AtrioventricularNode | 90.1 | |
| BDCA4+_DentriticCells | 55.5 | |
| Bonemarrow | 64.55 | |
| BronchialEpithelialCells | 39.1 | |
| CD105+_Endothelial | 84.1 | |
| CD14+_Monocytes | 45 | |
| CD19+_BCells(neg._sel.) | 58.45 | |
| CD33+_Myeloid | 41.15 | |
| CD34+ | 68.8 | |
| CD4+_Tcells | 52.45 | |
| CD56+_NKCells | 46.35 | |
| CD71+_EarlyErythroid | 44.7 | |
| CD8+_Tcells | 45.7 | |
| CardiacMyocytes | 35 | |
| Caudatenucleus | 44.15 | |
| Cerebellum | 43.6 | |
| CerebellumPeduncles | 65.8 | |
| CiliaryGanglion | 87.95 | |
| CingulateCortex | 52 | |
| Colorectaladenocarcinoma | 60.75 | |
| DorsalRootGanglion | 64.9 | |
| FetalThyroid | 49.3 | |
| Fetalbrain | 41.95 | |
| Fetalliver | 39.45 | |
| Fetallung | 28.5 | |
| GlobusPallidus | 49.6 | |
| Heart | 60.15 | |
| Hypothalamus | 36.65 | |
| Kidney | 47.2 | |
| Leukemia_chronicMyelogenousK-562 | 61.8 | |
| Leukemia_promyelocytic-HL-60 | 51.6 | |
| Leukemialymphoblastic(MOLT-4) | 53.45 | |
| Liver | 46.4 | |
| Lung | 61.8 | |
| Lymphnode | 43.95 | |
| Lymphoma_burkitts(Daudi) | 104.7 | |
| Lymphoma_burkitts(Raji) | 53.85 | |
| MedullaOblongata | 44.3 | |
| OccipitalLobe | 26.65 | |
| OlfactoryBulb | 38.75 | |
| Ovary | 48.7 | |
| Pancreas | 42.15 | |
| PancreaticIslet | 83.45 | |
| ParietalLobe | 50.35 | |
| Pituitary | 45.8 | |
| Placenta | 51.55 | |
| Pons | 68.95 | |
| PrefrontalCortex | 30.8 | |
| Prostate | 66.8 | |
| Salivarygland | 41.25 | |
| SkeletalMuscle | 85.25 | |
| Skin | 79.3 | |
| SmoothMuscle | 47.45 | |
| Spinalcord | 46.25 | |
| SubthalamicNucleus | 48.8 | |
| SuperiorCervicalGanglion | 45.95 | |
| TemporalLobe | 61 | |
| Testis | 42.95 | |
| TestisGermCell | 36.05 | |
| TestisIntersitial | 37.55 | |
| TestisLeydigCell | 47.15 | |
| TestisSeminiferousTubule | 65.1 | |
| Thalamus | 65.75 | |
| Thymus | 50.35 | |
| Thyroid | 67.65 | |
| Tongue | 59.55 | |
| Tonsil | 82.35 | |
| Trachea | 45.95 | |
| TrigeminalGanglion | 57.4 | |
| Uterus | 41.1 | |
| UterusCorpus | 44.5 | |
| WholeBlood | 17.9 | |
| Wholebrain | 20.5 | |
| colon | 9.55 | |
| pineal_day | 45.4 | |
| pineal_night | 41.34 | |
| retina | 40.825 | |
| small_intestine | 20.55 | |
- Probe name: CUST_4807_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.39 ± 0.99 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.01 ± 0.48 | |
| Basal Part of Pons | 3.27 ± 0.8 | |
| Cerebellar Cortex | 3.52 ± 0.64 | |
| Cerebellar Nuclei | 3.28 ± 0.49 | |
| Claustrum | 3.63 ± 0.54 | |
| Epithalamus | 2.71 ± 0.42 | |
| Frontal Lobe | 3.26 ± 0.67 | |
| Globus Pallidus | 3.16 ± 0.71 | |
| Hypothalamus | 3.01 ± 0.38 | |
| Insula | 3.19 ± 0.69 | |
| Limbic Lobe | 3.35 ± 0.71 | |
| Mesencephalon | 3.2 ± 0.55 | |
| Myelencephalon | 3.34 ± 0.7 | |
| Occipital Lobe | 3.28 ± 0.72 | |
| Parietal Lobe | 3.27 ± 0.56 | |
| Pontine Tegmentum | 3.2 ± 0.7 | |
| Striatum | 3.41 ± 0.9 | |
| Subthalamus | 3.67 ± 1.47 | |
| Temporal Lobe | 3.23 ± 0.66 | |
| Thalamus | 3.41 ± 0.7 | |
| White Matter | 2.79 ± 0.16 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Grwd1 | CB | Cerebellum | 0.5 | |
| 1.12 | | |||
| Grwd1 | CTX | Cerebral cortex | 0.34 | |
| 0.64 | | |||
| Grwd1 | HIP | Hippocampal region | 2.27 | |
| 2.05 | | |||
| Grwd1 | HPF | Hippocampal formation | 2.39 | |
| 2.03 | | |||
| Grwd1 | HY | Hypothalamus | 2.49 | |
| 2.67 | | |||
| Grwd1 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Grwd1 | MB | Midbrain | 0.4 | |
| 0.89 | | |||
| Grwd1 | MY | Medulla | 1.49 | |
| 3.24 | | |||
| Grwd1 | OLF | Olfactory bulb | 8.5 | |
| 8.69 | | |||
| Grwd1 | P | Pons | 2.64 | |
| 4.49 | | |||
| Grwd1 | PAL | Pallidum | 0.25 | |
| 0.51 | | |||
| Grwd1 | RHP | Retrohippocampal region | 2.79 | |
| 2.19 | | |||
| Grwd1 | sAMY | Striatum-like amygdalar nuclei | 1.09 | |
| 0.86 | | |||
| Grwd1 | STR | Striatum | 0.73 | |
| 0.96 | | |||
| Grwd1 | STRd | Striatum dorsal region | 0.08 | |
| 0.1 | | |||
| Grwd1 | STRv | Striatum ventral region | 2.93 | |
| 3.86 | | |||
| Grwd1 | TH | Thalamus | 0.31 | |
| 0.28 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00000223 | 21 | 298 | 318 | ACMLTTATAHDGDVNVISWSR | Peptide Atlas |