AutismKB 2.0

Annotation Detail for NME5


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Basic Information Top
Gene Symbol:NME5 ( NM23-H5,NM23H5,RSPH23 )
Gene Full Name: non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Band: 5q31.2
Quick LinksEntrez ID:8382; OMIM: 603575; Uniprot ID:NDK5_HUMAN; ENSEMBL ID: ENSG00000112981; HGNC ID: 7853
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal50 / 336030714
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney8 / 21177737
larynx1 / 2414541
liver1 / 2077434
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid6 / 20539292
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206197_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte6.2
AdrenalCortex7.05
Adrenalgland5.45
Amygdala11.55
Appendix7.5
AtrioventricularNode4.9
BDCA4+_DentriticCells6.25
Bonemarrow6.3
BronchialEpithelialCells6.15
CD105+_Endothelial6.2
CD14+_Monocytes6.55
CD19+_BCells(neg._sel.)6.35
CD33+_Myeloid7.55
CD34+7.5
CD4+_Tcells6.35
CD56+_NKCells6.9
CD71+_EarlyErythroid5.85
CD8+_Tcells5.75
CardiacMyocytes9.1
Caudatenucleus6.8
Cerebellum5.15
CerebellumPeduncles7.4
CiliaryGanglion5
CingulateCortex7.1
Colorectaladenocarcinoma6.3
DorsalRootGanglion5.1
FetalThyroid6.25
Fetalbrain6.4
Fetalliver5.45
Fetallung5.65
GlobusPallidus8.8
Heart8.1
Hypothalamus13.15
Kidney5.4
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.55
Leukemialymphoblastic(MOLT-4)4.95
Liver8.5
Lung6.85
Lymphnode5.3
Lymphoma_burkitts(Daudi)8.1
Lymphoma_burkitts(Raji)9.35
MedullaOblongata10.1
OccipitalLobe8.55
OlfactoryBulb4.95
Ovary4.4
Pancreas5.2
PancreaticIslet6.75
ParietalLobe6.9
Pituitary11
Placenta6.25
Pons8.55
PrefrontalCortex10.65
Prostate7.35
Salivarygland5.1
SkeletalMuscle7.9
Skin5.8
SmoothMuscle7.05
Spinalcord6.8
SubthalamicNucleus6.35
SuperiorCervicalGanglion8.4
TemporalLobe8.1
Testis96.1
TestisGermCell88.8
TestisIntersitial326.35
TestisLeydigCell174.3
TestisSeminiferousTubule168.9
Thalamus6.9
Thymus4.8
Thyroid8.1
Tongue6.3
Tonsil6.2
Trachea5.55
TrigeminalGanglion6.95
Uterus5.15
UterusCorpus5.8
WholeBlood6.8
Wholebrain7.25
colon6.35
pineal_day12.18
pineal_night9.58
retina7.55
small_intestine5.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1298_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.77 ± 0.29
Basal Forebrain7.54 ± 0.12
Basal Part of Pons7.86 ± 0.28
Cerebellar Cortex7.48 ± 0.25
Cerebellar Nuclei7.41 ± 0.29
Claustrum7.35 ± 0.36
Epithalamus8.66 ± 0.67
Frontal Lobe7.63 ± 0.32
Globus Pallidus6.93 ± 0.33
Hypothalamus7.48 ± 0.12
Insula7.67 ± 0.26
Limbic Lobe7.78 ± 0.47
Mesencephalon7.62 ± 0.41
Myelencephalon7.66 ± 0.44
Occipital Lobe8.09 ± 0.34
Parietal Lobe7.78 ± 0.35
Pontine Tegmentum7.53 ± 0.38
Striatum8.06 ± 0.36
Subthalamus7.46 ± 0.18
Temporal Lobe7.75 ± 0.3
Thalamus7.48 ± 0.23
White Matter5.97 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nme5CBCerebellum4.07
3.82
Nme5CTXCerebral cortex8.29
4.78
Nme5HIPHippocampal region2.71
2.27
Nme5HPFHippocampal formation2.76
2.18
Nme5HYHypothalamus1.4
0.71
Nme5LSXLateral septal complex4.76
2.38
Nme5MBMidbrain9
5.42
Nme5MYMedulla15.99
10.1
Nme5OLFOlfactory bulb4.84
2.57
Nme5PPons14.14
7.68
Nme5PALPallidum0.95
0.63
Nme5RHPRetrohippocampal region2.65
1.58
Nme5sAMYStriatum-like amygdalar nuclei0.32
0.15
Nme5STRStriatum1.54
1.13
Nme5STRdStriatum dorsal region1.69
1.33
Nme5STRvStriatum ventral region0.61
0.65
Nme5THThalamus3.76
2.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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