AutismKB 2.0

Annotation Detail for KLF16


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Basic Information Top
Gene Symbol:KLF16 ( BTEB4,DRRF,NSLP2 )
Gene Full Name: Kruppel-like factor 16
Band: 19p13.3
Quick LinksEntrez ID:83855; OMIM: 606139; Uniprot ID:KLF16_HUMAN; ENSEMBL ID: ENSG00000129911; HGNC ID: 16857
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal45 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor10 / 12494980
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain15 / 110098913
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye10 / 21105447
heart0 / 896260 
intestine13 / 23447255
kidney2 / 2117779
larynx0 / 241450 
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin11 / 21057452
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P16476
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.95 ± 0.51
Basal Forebrain6.94 ± 0.51
Basal Part of Pons6.57 ± 0.68
Cerebellar Cortex6.46 ± 0.7
Cerebellar Nuclei6.76 ± 0.44
Claustrum7.37 ± 0.78
Epithalamus5.94 ± 0.44
Frontal Lobe6.63 ± 0.63
Globus Pallidus7.5 ± 0.55
Hypothalamus6.53 ± 0.48
Insula6.69 ± 0.63
Limbic Lobe6.99 ± 0.66
Mesencephalon6.82 ± 0.65
Myelencephalon6.83 ± 0.68
Occipital Lobe6.72 ± 0.67
Parietal Lobe6.63 ± 0.67
Pontine Tegmentum6.6 ± 0.51
Striatum7.09 ± 0.64
Subthalamus5.92 ± 1.07
Temporal Lobe6.64 ± 0.64
Thalamus6.6 ± 0.51
White Matter7.15 ± 0.28
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KLF16_HUMAN_199 9 199 207 SDHLAKHAR PRIDE
PAp00068240 26 89 114 GGPGAAPGGASPASSSSAASSPSSGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018