AutismKB 2.0

Annotation Detail for HDAC10


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HDAC10 ( DKFZp761B039,HD10,MGC149722 )
Gene Full Name: histone deacetylase 10
Band: 22q13.33
Quick LinksEntrez ID:83933; OMIM: 608544; Uniprot ID:HDA10_HUMAN; ENSEMBL ID: ENSG00000100429; HGNC ID: 18128
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia10 / 95842104
liver tumor21 / 96359217
lung tumor5 / 10312748
lymphoma12 / 71755167
non-neoplasia8 / 9725082
normal124 / 336030736
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood17 / 123478137
bone2 / 7165527
bone marrow2 / 4880140
brain30 / 110098927
cervix8 / 48171166
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye3 / 21105414
heart1 / 8962611
intestine11 / 23447246
kidney3 / 21177714
larynx0 / 241450 
liver22 / 207743105
lung8 / 33697423
lymph6 / 44270135
lymph node14 / 91610152
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate1 / 1893455
salivary gland1 / 2015549
skin4 / 21057418
spleen1 / 5395218
stomach6 / 9661962
testis2 / 3304426
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P368740
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.16 ± 0.65
Basal Forebrain4.16 ± 0.6
Basal Part of Pons4.23 ± 0.62
Cerebellar Cortex4.74 ± 0.52
Cerebellar Nuclei3.89 ± 0.53
Claustrum3.92 ± 0.82
Epithalamus3.9 ± 0.75
Frontal Lobe4.15 ± 0.65
Globus Pallidus3.28 ± 0.46
Hypothalamus4.2 ± 0.66
Insula4.38 ± 0.55
Limbic Lobe4.11 ± 0.64
Mesencephalon4.18 ± 0.66
Myelencephalon4.19 ± 0.67
Occipital Lobe4.46 ± 0.49
Parietal Lobe4.21 ± 0.51
Pontine Tegmentum4.1 ± 0.58
Striatum3.57 ± 0.63
Subthalamus3.86 ± 0.71
Temporal Lobe4.39 ± 0.52
Thalamus4.34 ± 0.63
White Matter2.64 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hdac10CBCerebellum0.84
1.8
Hdac10CTXCerebral cortex0.24
0.39
Hdac10HIPHippocampal region0.34
0.7
Hdac10HPFHippocampal formation0.25
0.53
Hdac10HYHypothalamus0.12
0.14
Hdac10LSXLateral septal complex0
0
Hdac10MBMidbrain0.25
0.37
Hdac10MYMedulla0.36
0.41
Hdac10OLFOlfactory bulb0.21
0.33
Hdac10PPons0.16
0.26
Hdac10PALPallidum0.11
0.1
Hdac10RHPRetrohippocampal region0.12
0.27
Hdac10sAMYStriatum-like amygdalar nuclei0.11
0.11
Hdac10STRStriatum0.09
0.12
Hdac10STRdStriatum dorsal region0.06
0.1
Hdac10STRvStriatum ventral region0.22
0.21
Hdac10THThalamus0.12
0.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018