AutismKB 2.0

Annotation Detail for RASSF4


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Basic Information Top
Gene Symbol:RASSF4 ( AD037,MGC44914 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family member 4
Band: 10q11.21
Quick LinksEntrez ID:83937; OMIM: 610559; Uniprot ID:RASF4_HUMAN; ENSEMBL ID: ENSG00000107551; HGNC ID: 20793
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult89 / 193912145
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 49306_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.05
Adipocyte12
AdrenalCortex6.95
Adrenalgland5.6
Amygdala7.95
Appendix6.75
AtrioventricularNode5.1
BDCA4+_DentriticCells11.55
Bonemarrow6.5
BronchialEpithelialCells6
CD105+_Endothelial6.9
CD14+_Monocytes134.05
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid261.2
CD34+8.45
CD4+_Tcells7.25
CD56+_NKCells50.7
CD71+_EarlyErythroid6.2
CD8+_Tcells5.35
CardiacMyocytes8.35
Caudatenucleus6.75
Cerebellum5.5
CerebellumPeduncles10
CiliaryGanglion4.75
CingulateCortex9.15
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.8
FetalThyroid13
Fetalbrain6.7
Fetalliver5.7
Fetallung5.45
GlobusPallidus4.95
Heart9.7
Hypothalamus7.6
Kidney12.1
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.3
Liver8.8
Lung8.5
Lymphnode7.7
Lymphoma_burkitts(Daudi)8.45
Lymphoma_burkitts(Raji)9.4
MedullaOblongata6.2
OccipitalLobe6.1
OlfactoryBulb5.35
Ovary4.4
Pancreas5.35
PancreaticIslet7.2
ParietalLobe7.8
Pituitary7.95
Placenta6.65
Pons6.35
PrefrontalCortex9.05
Prostate7.65
Salivarygland5.35
SkeletalMuscle7.35
Skin5.1
SmoothMuscle7.3
Spinalcord8.85
SubthalamicNucleus6.1
SuperiorCervicalGanglion7.5
TemporalLobe6.9
Testis5.8
TestisGermCell5.25
TestisIntersitial5.6
TestisLeydigCell6.55
TestisSeminiferousTubule5.7
Thalamus6.85
Thymus5.5
Thyroid33.4
Tongue6.45
Tonsil6.6
Trachea5.4
TrigeminalGanglion6.5
Uterus5.25
UterusCorpus5.9
WholeBlood6.95
Wholebrain7.6
colon6.8
pineal_day11.64
pineal_night9.58
retina9.3
small_intestine6.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75260
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.23 ± 0.35
Basal Forebrain10.45 ± 0.45
Basal Part of Pons10.27 ± 0.38
Cerebellar Cortex10.54 ± 0.22
Cerebellar Nuclei10.93 ± 0.21
Claustrum10.25 ± 0.27
Epithalamus10.55 ± 0.47
Frontal Lobe10.17 ± 0.35
Globus Pallidus11.63 ± 0.38
Hypothalamus10.43 ± 0.36
Insula10.11 ± 0.34
Limbic Lobe10.07 ± 0.5
Mesencephalon10.65 ± 0.37
Myelencephalon10.48 ± 0.38
Occipital Lobe11.02 ± 0.55
Parietal Lobe10.55 ± 0.42
Pontine Tegmentum10.49 ± 0.41
Striatum10.22 ± 0.49
Subthalamus10.69 ± 0.36
Temporal Lobe10.33 ± 0.39
Thalamus10.91 ± 0.31
White Matter11.34 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rassf4CBCerebellum1.94
2.71
Rassf4CTXCerebral cortex1.39
1.79
Rassf4HIPHippocampal region1.71
2.36
Rassf4HPFHippocampal formation1.09
1.37
Rassf4HYHypothalamus0.57
0.47
Rassf4LSXLateral septal complex0.52
0.44
Rassf4MBMidbrain3.14
4.24
Rassf4MYMedulla8.41
10.02
Rassf4OLFOlfactory bulb8.68
7.4
Rassf4PPons6.26
7.59
Rassf4PALPallidum2.09
1.88
Rassf4RHPRetrohippocampal region0.38
0.38
Rassf4sAMYStriatum-like amygdalar nuclei0.58
0.38
Rassf4STRStriatum1.15
1.47
Rassf4STRdStriatum dorsal region0.44
0.64
Rassf4STRvStriatum ventral region2
2.32
Rassf4THThalamus0.72
1.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018