AutismKB 2.0

Annotation Detail for RASSF4


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Basic Information Top
Gene Symbol:RASSF4 ( AD037,MGC44914 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family member 4
Band: 10q11.21
Quick LinksEntrez ID:83937; OMIM: 610559; Uniprot ID:RASF4_HUMAN; ENSEMBL ID: ENSG00000107551; HGNC ID: 20793
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma11 / 106883102
head and neck tumor15 / 136302110
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal138 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone2 / 7165527
bone marrow0 / 488010 
brain78 / 110098970
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye15 / 21105471
heart7 / 8962678
intestine4 / 23447217
kidney13 / 21177761
larynx1 / 2414541
liver6 / 20774328
lung12 / 33697435
lymph2 / 4427045
lymph node2 / 9161021
mammary gland3 / 15327119
mouth7 / 67052104
muscle4 / 10771537
nerve3 / 15768190
ovary3 / 10205129
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate0 / 1893450 
salivary gland4 / 20155198
skin4 / 21057418
spleen9 / 53952166
stomach2 / 9661920
testis1 / 3304423
thymus1 / 8113112
thyroid10 / 47473210
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 49306_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.05
Adipocyte12
AdrenalCortex6.95
Adrenalgland5.6
Amygdala7.95
Appendix6.75
AtrioventricularNode5.1
BDCA4+_DentriticCells11.55
Bonemarrow6.5
BronchialEpithelialCells6
CD105+_Endothelial6.9
CD14+_Monocytes134.05
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid261.2
CD34+8.45
CD4+_Tcells7.25
CD56+_NKCells50.7
CD71+_EarlyErythroid6.2
CD8+_Tcells5.35
CardiacMyocytes8.35
Caudatenucleus6.75
Cerebellum5.5
CerebellumPeduncles10
CiliaryGanglion4.75
CingulateCortex9.15
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.8
FetalThyroid13
Fetalbrain6.7
Fetalliver5.7
Fetallung5.45
GlobusPallidus4.95
Heart9.7
Hypothalamus7.6
Kidney12.1
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.3
Liver8.8
Lung8.5
Lymphnode7.7
Lymphoma_burkitts(Daudi)8.45
Lymphoma_burkitts(Raji)9.4
MedullaOblongata6.2
OccipitalLobe6.1
OlfactoryBulb5.35
Ovary4.4
Pancreas5.35
PancreaticIslet7.2
ParietalLobe7.8
Pituitary7.95
Placenta6.65
Pons6.35
PrefrontalCortex9.05
Prostate7.65
Salivarygland5.35
SkeletalMuscle7.35
Skin5.1
SmoothMuscle7.3
Spinalcord8.85
SubthalamicNucleus6.1
SuperiorCervicalGanglion7.5
TemporalLobe6.9
Testis5.8
TestisGermCell5.25
TestisIntersitial5.6
TestisLeydigCell6.55
TestisSeminiferousTubule5.7
Thalamus6.85
Thymus5.5
Thyroid33.4
Tongue6.45
Tonsil6.6
Trachea5.4
TrigeminalGanglion6.5
Uterus5.25
UterusCorpus5.9
WholeBlood6.95
Wholebrain7.6
colon6.8
pineal_day11.64
pineal_night9.58
retina9.3
small_intestine6.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75260
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.23 ± 0.35
Basal Forebrain10.45 ± 0.45
Basal Part of Pons10.27 ± 0.38
Cerebellar Cortex10.54 ± 0.22
Cerebellar Nuclei10.93 ± 0.21
Claustrum10.25 ± 0.27
Epithalamus10.55 ± 0.47
Frontal Lobe10.17 ± 0.35
Globus Pallidus11.63 ± 0.38
Hypothalamus10.43 ± 0.36
Insula10.11 ± 0.34
Limbic Lobe10.07 ± 0.5
Mesencephalon10.65 ± 0.37
Myelencephalon10.48 ± 0.38
Occipital Lobe11.02 ± 0.55
Parietal Lobe10.55 ± 0.42
Pontine Tegmentum10.49 ± 0.41
Striatum10.22 ± 0.49
Subthalamus10.69 ± 0.36
Temporal Lobe10.33 ± 0.39
Thalamus10.91 ± 0.31
White Matter11.34 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rassf4CBCerebellum1.94
2.71
Rassf4CTXCerebral cortex1.39
1.79
Rassf4HIPHippocampal region1.71
2.36
Rassf4HPFHippocampal formation1.09
1.37
Rassf4HYHypothalamus0.57
0.47
Rassf4LSXLateral septal complex0.52
0.44
Rassf4MBMidbrain3.14
4.24
Rassf4MYMedulla8.41
10.02
Rassf4OLFOlfactory bulb8.68
7.4
Rassf4PPons6.26
7.59
Rassf4PALPallidum2.09
1.88
Rassf4RHPRetrohippocampal region0.38
0.38
Rassf4sAMYStriatum-like amygdalar nuclei0.58
0.38
Rassf4STRStriatum1.15
1.47
Rassf4STRdStriatum dorsal region0.44
0.64
Rassf4STRvStriatum ventral region2
2.32
Rassf4THThalamus0.72
1.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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