AutismKB 2.0

Annotation Detail for PLA2G6


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Basic Information Top
Gene Symbol:PLA2G6 ( CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2 )
Gene Full Name: phospholipase A2, group VI (cytosolic, calcium-independent)
Band: 22q13.1
Quick LinksEntrez ID:8398; OMIM: 603604; Uniprot ID:PA2G6_HUMAN; ENSEMBL ID: ENSG00000184381; HGNC ID: 9039
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus35 / 56401262
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor17 / 26384564
glioma4 / 10688337
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal201 / 336030759
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood3 / 12347824
bone1 / 7165513
bone marrow1 / 4880120
brain117 / 1100989106
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland7 / 15327145
mouth6 / 6705289
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate7 / 18934536
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach2 / 9661920
testis87 / 330442263
thymus29 / 81131357
thyroid0 / 474730 
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus25 / 232878107
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215938_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.1
AdrenalCortex5.65
Adrenalgland4.35
Amygdala5.5
Appendix5.15
AtrioventricularNode4.2
BDCA4+_DentriticCells5.65
Bonemarrow5.05
BronchialEpithelialCells5.1
CD105+_Endothelial5.2
CD14+_Monocytes5
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid6.25
CD34+7.85
CD4+_Tcells5.8
CD56+_NKCells10.65
CD71+_EarlyErythroid4.85
CD8+_Tcells7.25
CardiacMyocytes6.5
Caudatenucleus4.7
Cerebellum4.7
CerebellumPeduncles5.85
CiliaryGanglion3.7
CingulateCortex5.05
Colorectaladenocarcinoma4.8
DorsalRootGanglion4.05
FetalThyroid6.55
Fetalbrain5.5
Fetalliver4.2
Fetallung4.15
GlobusPallidus5.65
Heart6.45
Hypothalamus5.6
Kidney4.05
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)4
Liver6.65
Lung6.1
Lymphnode5.35
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)14.4
MedullaOblongata4.75
OccipitalLobe4.8
OlfactoryBulb4.05
Ovary3.4
Pancreas4.15
PancreaticIslet5.5
ParietalLobe7.55
Pituitary6.05
Placenta4.95
Pons6.85
PrefrontalCortex8.95
Prostate6.1
Salivarygland4.05
SkeletalMuscle6.1
Skin4.05
SmoothMuscle5.6
Spinalcord5.55
SubthalamicNucleus4.6
SuperiorCervicalGanglion8.9
TemporalLobe4.75
Testis26.95
TestisGermCell9
TestisIntersitial7.6
TestisLeydigCell5.3
TestisSeminiferousTubule5.2
Thalamus5.25
Thymus4.1
Thyroid6.6
Tongue8.05
Tonsil7.05
Trachea4.35
TrigeminalGanglion5.3
Uterus4.25
UterusCorpus5.4
WholeBlood5.15
Wholebrain4.95
colon5.2
pineal_day11.14
pineal_night7.46
retina5.825
small_intestine4.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16677_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.91 ± 0.82
Basal Forebrain3.78 ± 0.57
Basal Part of Pons4.13 ± 0.72
Cerebellar Cortex4.12 ± 0.52
Cerebellar Nuclei3.6 ± 0.56
Claustrum3.59 ± 0.68
Epithalamus3.92 ± 0.83
Frontal Lobe3.93 ± 0.61
Globus Pallidus3.22 ± 0.74
Hypothalamus3.55 ± 0.56
Insula3.85 ± 0.54
Limbic Lobe3.7 ± 0.74
Mesencephalon3.63 ± 0.6
Myelencephalon3.78 ± 0.66
Occipital Lobe3.48 ± 0.6
Parietal Lobe3.8 ± 0.65
Pontine Tegmentum3.65 ± 0.63
Striatum3.17 ± 0.68
Subthalamus3.74 ± 0.42
Temporal Lobe3.94 ± 0.56
Thalamus3.7 ± 0.69
White Matter4.39 ± 0.69
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018