AutismKB 2.0

Annotation Detail for KREMEN1


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Basic Information Top
Gene Symbol:KREMEN1 ( FLJ31863,KREMEN,KRM1 )
Gene Full Name: kringle containing transmembrane protein 1
Band: 22q12.1
Quick LinksEntrez ID:83999; OMIM: 609898; Uniprot ID:KREM1_HUMAN; ENSEMBL ID: ENSG00000183762; HGNC ID: 17550
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus20 / 56401235
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor11 / 26384541
glioma2 / 10688318
head and neck tumor19 / 136302139
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal111 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine9 / 23447238
kidney9 / 21177742
larynx2 / 2414582
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth18 / 67052268
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin34 / 210574161
spleen0 / 539520 
stomach6 / 9661962
testis11 / 33044233
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P211401
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.55 ± 0.92
Basal Forebrain2.02 ± 0.43
Basal Part of Pons1.89 ± 0.39
Cerebellar Cortex1.82 ± 0.49
Cerebellar Nuclei2.17 ± 0.63
Claustrum2.37 ± 0.66
Epithalamus1.79 ± 0.84
Frontal Lobe2.06 ± 0.72
Globus Pallidus1.85 ± 0.44
Hypothalamus2.05 ± 0.87
Insula1.66 ± 0.67
Limbic Lobe2.15 ± 0.71
Mesencephalon2.27 ± 0.83
Myelencephalon2.24 ± 0.76
Occipital Lobe2.51 ± 0.91
Parietal Lobe2.14 ± 0.74
Pontine Tegmentum2.21 ± 0.77
Striatum3.67 ± 0.44
Subthalamus2.2 ± 0.78
Temporal Lobe2.03 ± 0.76
Thalamus2.09 ± 0.7
White Matter1.93 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018