Annotation Detail for OBSCN
Basic Information Top
| Gene Symbol: | OBSCN ( ARHGEF30,DKFZp666E245,FLJ14124,KIAA1556,KIAA1639,MGC120409,MGC120410,MGC120411,MGC120412,MGC138590,UNC89 ) |
|---|---|
| Gene Full Name: | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| Band: | 1q42.13 |
| Quick Links | Entrez ID:84033; OMIM: 608616; Uniprot ID:OBSCN_HUMAN; ENSEMBL ID: ENSG00000154358; HGNC ID: 15719 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.656999
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 14 / 564012 | 24 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 76 / 1939121 | 39 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 88 / 3360307 | 26 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 8 / 90257 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 20 / 1100989 | 18 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 5 / 89626 | 55 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 10 / 24145 | 414 |  |
| liver | 0 / 207743 | 0 | |
| lung | 6 / 336974 | 17 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 21 / 107715 | 194 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 10 / 330442 | 30 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_12120_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.43 ± 1.33 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.66 ± 0.61 | |
| Basal Part of Pons | 2.26 ± 0.61 | |
| Cerebellar Cortex | 3.49 ± 0.59 | |
| Cerebellar Nuclei | 3.04 ± 0.49 | |
| Claustrum | 3.54 ± 0.97 | |
| Epithalamus | 2.79 ± 0.68 | |
| Frontal Lobe | 2.69 ± 0.93 | |
| Globus Pallidus | 2.97 ± 0.82 | |
| Hypothalamus | 2.54 ± 0.58 | |
| Insula | 2.38 ± 0.87 | |
| Limbic Lobe | 2.87 ± 0.9 | |
| Mesencephalon | 3.38 ± 0.91 | |
| Myelencephalon | 3.11 ± 1.01 | |
| Occipital Lobe | 2.91 ± 0.95 | |
| Parietal Lobe | 2.98 ± 1.12 | |
| Pontine Tegmentum | 3.23 ± 1.13 | |
| Striatum | 4.85 ± 1.02 | |
| Subthalamus | 2.77 ± 1.07 | |
| Temporal Lobe | 2.89 ± 0.84 | |
| Thalamus | 2.9 ± 0.94 | |
| White Matter | 1.82 ± 0.15 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Obscn | CB | Cerebellum | 7.33 | |
| 8.69 | | |||
| Obscn | CTX | Cerebral cortex | 8.01 | |
| 6.38 | | |||
| Obscn | HIP | Hippocampal region | 7.16 | |
| 7.28 | | |||
| Obscn | HPF | Hippocampal formation | 7.21 | |
| 6.59 | | |||
| Obscn | HY | Hypothalamus | 4.3 | |
| 4.77 | | |||
| Obscn | LSX | Lateral septal complex | 0.2 | |
| 0.14 | | |||
| Obscn | MB | Midbrain | 2.7 | |
| 3.51 | | |||
| Obscn | MY | Medulla | 5.98 | |
| 7.03 | | |||
| Obscn | OLF | Olfactory bulb | 10.63 | |
| 7.99 | | |||
| Obscn | P | Pons | 4.48 | |
| 4.66 | | |||
| Obscn | PAL | Pallidum | 4.99 | |
| 3.97 | | |||
| Obscn | RHP | Retrohippocampal region | 7.5 | |
| 5.61 | | |||
| Obscn | sAMY | Striatum-like amygdalar nuclei | 1.05 | |
| 0.81 | | |||
| Obscn | STR | Striatum | 9.56 | |
| 7.16 | | |||
| Obscn | STRd | Striatum dorsal region | 12.94 | |
| 9.83 | | |||
| Obscn | STRv | Striatum ventral region | 7.06 | |
| 4.78 | | |||
| Obscn | TH | Thalamus | 6.69 | |
| 6.49 | |