AutismKB 2.0

Annotation Detail for SPARCL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SPARCL1 ( PIG33,SC1 )
Gene Full Name: SPARC-like 1 (hevin)
Band: 4q22.1
Quick LinksEntrez ID:8404; OMIM: 606041; Uniprot ID:SPRL1_HUMAN; ENSEMBL ID: ENSG00000152583; HGNC ID: 11220
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus183 / 564012324
neonate1 / 3109732
infant11 / 23620465
juvenile8 / 55556143
adult515 / 1939121265
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor6 / 11424652
esophageal tumor8 / 17290462
gastrointestinal tumor27 / 119369226
germ cell tumor3 / 26384511
glioma19 / 106883177
head and neck tumor23 / 136302168
kidney tumor25 / 68959362
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia114 / 972501172
normal2052 / 3360307610
ovarian tumor8 / 76682104
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue19 / 131061449
adrenal gland12 / 33197361
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain1733 / 11009891574
cervix9 / 48171186
connective tissue68 / 149255455
ear5 / 16212308
embryonic tissue4 / 21572218
esophagus15 / 20209742
eye42 / 211054199
heart93 / 896261037
intestine89 / 234472379
kidney39 / 211777184
larynx3 / 24145124
liver5 / 20774324
lung80 / 336974237
lymph2 / 4427045
lymph node0 / 916100 
mammary gland5 / 15327132
mouth22 / 67052328
muscle22 / 107715204
nerve14 / 15768887
ovary12 / 102051117
pancreas20 / 21481293
parathyroid6 / 20539292
pharynx5 / 41328120
pituitary gland12 / 16585723
placenta62 / 280825220
prostate66 / 189345348
salivary gland0 / 201550 
skin1 / 2105744
spleen52 / 53952963
stomach59 / 96619610
testis45 / 330442136
thymus36 / 81131443
thyroid15 / 47473315
tonsil0 / 169990 
trachea48 / 52413915
umbilical cord0 / 136800 
uterus435 / 2328781867
vascular46 / 51780888
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200795_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.7
Adipocyte157.35
AdrenalCortex298.05
Adrenalgland184.85
Amygdala7706.1
Appendix3031.15
AtrioventricularNode974.45
BDCA4+_DentriticCells4.95
Bonemarrow9.75
BronchialEpithelialCells5.2
CD105+_Endothelial21.5
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5
CD33+_Myeloid7.05
CD34+6.4
CD4+_Tcells5.25
CD56+_NKCells5.4
CD71+_EarlyErythroid5.1
CD8+_Tcells4.4
CardiacMyocytes7
Caudatenucleus5927.65
Cerebellum327.65
CerebellumPeduncles1030.45
CiliaryGanglion1024.65
CingulateCortex4987.55
Colorectaladenocarcinoma6
DorsalRootGanglion1147.1
FetalThyroid1436.75
Fetalbrain1390.1
Fetalliver4.85
Fetallung2131.05
GlobusPallidus4554.45
Heart69.45
Hypothalamus4600.25
Kidney18.5
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-60673.95
Leukemialymphoblastic(MOLT-4)5.95
Liver6.3
Lung353.6
Lymphnode1402.5
Lymphoma_burkitts(Daudi)12.4
Lymphoma_burkitts(Raji)476.8
MedullaOblongata6372.9
OccipitalLobe7822.05
OlfactoryBulb2818.1
Ovary1913.2
Pancreas511.3
PancreaticIslet885.4
ParietalLobe7084.1
Pituitary3147.15
Placenta111.1
Pons4465.05
PrefrontalCortex13155.55
Prostate991.75
Salivarygland758.15
SkeletalMuscle474.1
Skin473.55
SmoothMuscle6.25
Spinalcord7518.55
SubthalamicNucleus6470.85
SuperiorCervicalGanglion934.5
TemporalLobe5194.4
Testis154.8
TestisGermCell1565.55
TestisIntersitial980.55
TestisLeydigCell1004.05
TestisSeminiferousTubule617
Thalamus1593.45
Thymus153.15
Thyroid1417.05
Tongue652.7
Tonsil294.2
Trachea855.45
TrigeminalGanglion865.8
Uterus4827.95
UterusCorpus3187.35
WholeBlood7.3
Wholebrain2995.15
colon797.1
pineal_day2388.72
pineal_night2520.64
retina3273.875
small_intestine540.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P113351
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.15 ± 0.53
Basal Forebrain12.74 ± 0.59
Basal Part of Pons12.86 ± 0.4
Cerebellar Cortex11.72 ± 0.25
Cerebellar Nuclei12.29 ± 0.5
Claustrum12.32 ± 1.38
Epithalamus11.98 ± 0.45
Frontal Lobe12.7 ± 0.58
Globus Pallidus12.68 ± 0.56
Hypothalamus12.97 ± 0.25
Insula12.61 ± 0.42
Limbic Lobe12.43 ± 0.67
Mesencephalon12.55 ± 0.78
Myelencephalon12.45 ± 0.66
Occipital Lobe12.25 ± 0.66
Parietal Lobe12.74 ± 0.56
Pontine Tegmentum12.47 ± 0.56
Striatum12.98 ± 0.4
Subthalamus12.03 ± 0.14
Temporal Lobe12.4 ± 0.53
Thalamus11.51 ± 0.41
White Matter10.46 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sparcl1CBCerebellum100
100
Sparcl1CTXCerebral cortex100
100
Sparcl1HIPHippocampal region100
100
Sparcl1HPFHippocampal formation100
100
Sparcl1HYHypothalamus100
100
Sparcl1LSXLateral septal complex100
100
Sparcl1MBMidbrain100
100
Sparcl1MYMedulla100
100
Sparcl1OLFOlfactory bulb100
100
Sparcl1PPons100
100
Sparcl1PALPallidum100
100
Sparcl1RHPRetrohippocampal region100
100
Sparcl1sAMYStriatum-like amygdalar nuclei100
100
Sparcl1STRStriatum100
100
Sparcl1STRdStriatum dorsal region97.53
100
Sparcl1STRvStriatum ventral region100
100
Sparcl1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092843 13 287 299 HIQETEWQSQEGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved