AutismKB 2.0

Annotation Detail for GPR98


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Basic Information Top
Gene Symbol:GPR98 ( DKFZp761P0710,FEB4,KIAA0686,MASS1,USH2B,USH2C,VLGR1,VLGR1b )
Gene Full Name: G protein-coupled receptor 98
Band: 5q13
Quick LinksEntrez ID:84059; OMIM: 602851; Uniprot ID:GPR98_HUMAN; ENSEMBL ID: ENSG00000164199; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal82 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain50 / 110098945
cervix0 / 481710 
connective tissue32 / 149255214
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_299_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.82 ± 0.57
Basal Forebrain6.21 ± 0.42
Basal Part of Pons4.7 ± 0.52
Cerebellar Cortex4.46 ± 0.54
Cerebellar Nuclei4.24 ± 0.43
Claustrum5.74 ± 0.64
Epithalamus5.39 ± 0.96
Frontal Lobe5.14 ± 0.75
Globus Pallidus3.24 ± 1.86
Hypothalamus5.11 ± 0.83
Insula5.72 ± 0.6
Limbic Lobe5.86 ± 0.63
Mesencephalon5.05 ± 0.83
Myelencephalon5.15 ± 0.82
Occipital Lobe5.09 ± 0.61
Parietal Lobe5 ± 0.95
Pontine Tegmentum5.15 ± 0.81
Striatum6.73 ± 0.47
Subthalamus4.62 ± 0.88
Temporal Lobe5.38 ± 0.74
Thalamus4.05 ± 0.78
White Matter3.63 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr98CBCerebellum1.45
1.98
Gpr98CTXCerebral cortex0.65
0.67
Gpr98HIPHippocampal region1.91
1.98
Gpr98HPFHippocampal formation1.26
1.25
Gpr98HYHypothalamus1.08
1.01
Gpr98LSXLateral septal complex1.57
1.65
Gpr98MBMidbrain1.24
1.69
Gpr98MYMedulla1.01
1.2
Gpr98OLFOlfactory bulb0.89
0.93
Gpr98PPons0.84
1.22
Gpr98PALPallidum0.43
0.38
Gpr98RHPRetrohippocampal region0.35
0.36
Gpr98sAMYStriatum-like amygdalar nuclei0.28
0.55
Gpr98STRStriatum0.63
0.66
Gpr98STRdStriatum dorsal region0.44
0.51
Gpr98STRvStriatum ventral region1.05
0.77
Gpr98THThalamus0.75
1.02
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018