AutismKB 2.0

Annotation Detail for ULK1


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Basic Information Top
Gene Symbol:ULK1 ( ATG1,ATG1A,FLJ38455,FLJ46475,UNC51,Unc51.1 )
Gene Full Name: unc-51-like kinase 1 (C. elegans)
Band: 12q24.33
Quick LinksEntrez ID:8408; OMIM: 603168; Uniprot ID:ULK1_HUMAN; ENSEMBL ID: ENSG00000177169; HGNC ID: 12558
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst6 / 6231996
fetus25 / 56401244
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor12 / 26384545
glioma13 / 106883121
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia9 / 9584293
liver tumor0 / 963590 
lung tumor10 / 10312796
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal158 / 336030747
ovarian tumor7 / 7668291
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder1 / 2975733
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain63 / 110098957
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye10 / 21105447
heart8 / 8962689
intestine16 / 23447268
kidney12 / 21177756
larynx1 / 2414541
liver0 / 2077430 
lung23 / 33697468
lymph0 / 442700 
lymph node3 / 9161032
mammary gland6 / 15327139
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary18 / 102051176
pancreas20 / 21481293
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate6 / 18934531
salivary gland1 / 2015549
skin9 / 21057442
spleen4 / 5395274
stomach0 / 966190 
testis13 / 33044239
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209333_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte4.4
AdrenalCortex4.6
Adrenalgland4.6
Amygdala9.7
Appendix4.35
AtrioventricularNode3.25
BDCA4+_DentriticCells42.65
Bonemarrow4.4
BronchialEpithelialCells4.2
CD105+_Endothelial4.5
CD14+_Monocytes8.35
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid22.5
CD34+9.05
CD4+_Tcells5
CD56+_NKCells5.6
CD71+_EarlyErythroid12.15
CD8+_Tcells4.45
CardiacMyocytes5.75
Caudatenucleus19.35
Cerebellum6.85
CerebellumPeduncles5.1
CiliaryGanglion3.05
CingulateCortex4.65
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.35
FetalThyroid4.4
Fetalbrain5.9
Fetalliver3.95
Fetallung4.2
GlobusPallidus4.9
Heart12.8
Hypothalamus6.75
Kidney3.6
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)6.3
Liver5.95
Lung5
Lymphnode3.95
Lymphoma_burkitts(Daudi)5.45
Lymphoma_burkitts(Raji)6.2
MedullaOblongata4.3
OccipitalLobe4.05
OlfactoryBulb3.5
Ovary2.9
Pancreas3.55
PancreaticIslet4.9
ParietalLobe4.75
Pituitary5.8
Placenta17.65
Pons4.3
PrefrontalCortex11.95
Prostate5.4
Salivarygland3.4
SkeletalMuscle5.2
Skin3.4
SmoothMuscle5
Spinalcord4.65
SubthalamicNucleus6.1
SuperiorCervicalGanglion4.95
TemporalLobe4.05
Testis3.9
TestisGermCell3.8
TestisIntersitial3.65
TestisLeydigCell4.35
TestisSeminiferousTubule3.85
Thalamus5.25
Thymus5.2
Thyroid6.6
Tongue4.2
Tonsil4.35
Trachea3.7
TrigeminalGanglion4.3
Uterus11.2
UterusCorpus3.9
WholeBlood8.7
Wholebrain5.35
colon4.4
pineal_day9.06
pineal_night10.1
retina5.7
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P73370
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.08 ± 0.57
Basal Forebrain8.19 ± 0.48
Basal Part of Pons8.62 ± 0.17
Cerebellar Cortex8.25 ± 0.26
Cerebellar Nuclei7.82 ± 0.64
Claustrum7.74 ± 0.56
Epithalamus7.71 ± 0.27
Frontal Lobe8.15 ± 0.34
Globus Pallidus6.91 ± 0.29
Hypothalamus8.08 ± 0.38
Insula8.28 ± 0.29
Limbic Lobe8.2 ± 0.5
Mesencephalon7.9 ± 0.44
Myelencephalon8.1 ± 0.51
Occipital Lobe7.88 ± 0.51
Parietal Lobe8.22 ± 0.36
Pontine Tegmentum8.05 ± 0.38
Striatum8.77 ± 0.53
Subthalamus8.13 ± 0.25
Temporal Lobe8.39 ± 0.32
Thalamus8 ± 0.37
White Matter6.71 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ulk1CBCerebellum45.66
46.73
Ulk1CTXCerebral cortex24.92
17.26
Ulk1HIPHippocampal region22.49
21.91
Ulk1HPFHippocampal formation21.56
18.47
Ulk1HYHypothalamus4.92
3.9
Ulk1LSXLateral septal complex2.75
2.19
Ulk1MBMidbrain9.92
9.34
Ulk1MYMedulla30.11
30.54
Ulk1OLFOlfactory bulb28.49
21.69
Ulk1PPons15.56
16.65
Ulk1PALPallidum6.22
5.17
Ulk1RHPRetrohippocampal region19.92
14.06
Ulk1sAMYStriatum-like amygdalar nuclei11.49
8.5
Ulk1STRStriatum4.32
3.44
Ulk1STRdStriatum dorsal region3.48
2.97
Ulk1STRvStriatum ventral region4.13
3
Ulk1THThalamus6.52
5.7
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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