AutismKB 2.0

Annotation Detail for FBXO30


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Basic Information Top
Gene Symbol:FBXO30 ( FLJ41030,Fbx30,MGC21674 )
Gene Full Name: F-box protein 30
Band: 6q24.3
Quick LinksEntrez ID:84085; OMIM: 609101; Uniprot ID:FBX30_HUMAN; ENSEMBL ID: ENSG00000118496; HGNC ID: 15600
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus16 / 56401228
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal75 / 336030722
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine4 / 23447217
kidney5 / 21177723
larynx1 / 2414541
liver7 / 20774333
lung7 / 33697420
lymph1 / 4427022
lymph node6 / 9161065
mammary gland0 / 1532710 
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis17 / 33044251
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12096_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.65 ± 0.4
Basal Forebrain7.06 ± 0.32
Basal Part of Pons6.15 ± 0.29
Cerebellar Cortex6.6 ± 0.24
Cerebellar Nuclei6.79 ± 0.29
Claustrum7.19 ± 0.46
Epithalamus6.8 ± 0.28
Frontal Lobe6.44 ± 0.42
Globus Pallidus7.52 ± 0.2
Hypothalamus7.04 ± 0.29
Insula6.39 ± 0.41
Limbic Lobe6.46 ± 0.48
Mesencephalon6.93 ± 0.38
Myelencephalon6.67 ± 0.41
Occipital Lobe6.87 ± 0.42
Parietal Lobe6.63 ± 0.43
Pontine Tegmentum6.75 ± 0.31
Striatum6.7 ± 0.42
Subthalamus6.9 ± 0.08
Temporal Lobe6.48 ± 0.35
Thalamus6.68 ± 0.27
White Matter7.37 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo30CBCerebellum4.71
5.69
Fbxo30CTXCerebral cortex1.76
2.24
Fbxo30HIPHippocampal region0.6
0.64
Fbxo30HPFHippocampal formation0.58
0.6
Fbxo30HYHypothalamus0.48
0.72
Fbxo30LSXLateral septal complex0
0
Fbxo30MBMidbrain0.78
1.29
Fbxo30MYMedulla1.93
2.64
Fbxo30OLFOlfactory bulb12.78
13.84
Fbxo30PPons2.14
3.25
Fbxo30PALPallidum0.33
0.4
Fbxo30RHPRetrohippocampal region0.54
0.55
Fbxo30sAMYStriatum-like amygdalar nuclei0.66
1.01
Fbxo30STRStriatum0.33
0.38
Fbxo30STRdStriatum dorsal region0.24
0.25
Fbxo30STRvStriatum ventral region0.44
0.51
Fbxo30THThalamus0.39
0.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FBX30_HUMAN_113 18 113 130 DVDEVAQLDMALALQDQR PRIDE
PAp00077328 17 586 602 SFGVQPCVSTVLVEPAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018