AutismKB 2.0

Annotation Detail for FAM176A


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Basic Information Top
Gene Symbol:FAM176A ( FLJ13391,TMEM166 )
Gene Full Name: family with sequence similarity 176, member A
Band: 2p12
Quick LinksEntrez ID:84141; OMIM: NA; Uniprot ID:F176A_HUMAN; ENSEMBL ID: ENSG00000115363; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor8 / 9635983
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal73 / 336030721
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney15 / 21177770
larynx0 / 241450 
liver14 / 20774367
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta17 / 28082560
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12994_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.03 ± 0.99
Basal Forebrain1.55 ± 0.2
Basal Part of Pons1.28 ± 0.34
Cerebellar Cortex1.44 ± 0.71
Cerebellar Nuclei1.93 ± 0.79
Claustrum2.4 ± 0.76
Epithalamus1.32 ± 0.75
Frontal Lobe1.43 ± 0.58
Globus Pallidus2.2 ± 0.3
Hypothalamus1.62 ± 0.65
Insula1.45 ± 0.48
Limbic Lobe1.62 ± 0.63
Mesencephalon1.73 ± 0.65
Myelencephalon1.63 ± 0.64
Occipital Lobe1.69 ± 0.75
Parietal Lobe1.54 ± 0.68
Pontine Tegmentum1.67 ± 0.68
Striatum1.79 ± 0.56
Subthalamus1.79 ± 0.63
Temporal Lobe1.54 ± 0.67
Thalamus1.58 ± 0.59
White Matter2.11 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem166CBCerebellum6.23
9.95
Tmem166CTXCerebral cortex10.35
7.64
Tmem166HIPHippocampal region4.31
4.45
Tmem166HPFHippocampal formation3.62
3.38
Tmem166HYHypothalamus0.64
0.6
Tmem166LSXLateral septal complex1.75
1.22
Tmem166MBMidbrain1.39
1.7
Tmem166MYMedulla1.46
1.86
Tmem166OLFOlfactory bulb6.52
5.57
Tmem166PPons1.06
1.47
Tmem166PALPallidum1.9
1.53
Tmem166RHPRetrohippocampal region2.33
1.76
Tmem166sAMYStriatum-like amygdalar nuclei1.1
0.76
Tmem166STRStriatum2.72
2.03
Tmem166STRdStriatum dorsal region2.4
1.91
Tmem166STRvStriatum ventral region4.81
3.15
Tmem166THThalamus2.58
2.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018