Annotation Detail for PPP1R1B
Basic Information Top
| Gene Symbol: | PPP1R1B ( DARPP-32,DARPP32,FLJ20940 ) |
|---|---|
| Gene Full Name: | protein phosphatase 1, regulatory (inhibitor) subunit 1B |
| Band: | 17q12 |
| Quick Links | Entrez ID:84152; OMIM: 604399; Uniprot ID:PPR1B_HUMAN; ENSEMBL ID: ENSG00000131771; HGNC ID: 9287 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.286192
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 12 / 564012 | 21 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 132 / 1939121 | 68 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 28 / 114246 | 245 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 25 / 119369 | 209 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 116 / 3360307 | 34 | |
| ovarian tumor | 12 / 76682 | 156 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 11 / 90257 | 121 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 9 / 40015 | 224 | |
| bladder | 2 / 29757 | 67 | |
| blood | 1 / 123478 | 8 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 71 / 1100989 | 64 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 1 / 89626 | 11 | |
| intestine | 55 / 234472 | 234 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 1 / 24145 | 41 | |
| liver | 0 / 207743 | 0 | |
| lung | 3 / 336974 | 8 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 9 / 153271 | 58 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 14 / 102051 | 137 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 13 / 189345 | 68 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 24 / 96619 | 248 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 2 / 51780 | 38 | |
Microarray in - Probe name: CUST_12418_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.16 ± 0.99 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.74 ± 0.72 | |
| Basal Part of Pons | 4.3 ± 0.75 | |
| Cerebellar Cortex | 4.47 ± 0.22 | |
| Cerebellar Nuclei | 4.3 ± 0.58 | |
| Claustrum | 5.01 ± 0.8 | |
| Epithalamus | 5.89 ± 0.46 | |
| Frontal Lobe | 4.82 ± 0.55 | |
| Globus Pallidus | 5.68 ± 0.36 | |
| Hypothalamus | 4.49 ± 0.85 | |
| Insula | 5.11 ± 0.41 | |
| Limbic Lobe | 4.63 ± 0.57 | |
| Mesencephalon | 5.1 ± 0.92 | |
| Myelencephalon | 5.04 ± 0.81 | |
| Occipital Lobe | 4.63 ± 0.55 | |
| Parietal Lobe | 5.04 ± 0.6 | |
| Pontine Tegmentum | 5.13 ± 0.66 | |
| Striatum | 7.46 ± 0.79 | |
| Subthalamus | 4.79 ± 0.52 | |
| Temporal Lobe | 4.98 ± 0.52 | |
| Thalamus | 5.15 ± 0.62 | |
| White Matter | 3.51 ± 0.27 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ppp1r1b | CB | Cerebellum | 68.56 | |
| 100 | | |||
| Ppp1r1b | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Ppp1r1b | HIP | Hippocampal region | 70.21 | |
| 86.32 | | |||
| Ppp1r1b | HPF | Hippocampal formation | 80.89 | |
| 93.91 | | |||
| Ppp1r1b | HY | Hypothalamus | 53.02 | |
| 53.1 | | |||
| Ppp1r1b | LSX | Lateral septal complex | 79.06 | |
| 89.9 | | |||
| Ppp1r1b | MB | Midbrain | 62.07 | |
| 62.22 | | |||
| Ppp1r1b | MY | Medulla | 68.71 | |
| 74.29 | | |||
| Ppp1r1b | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Ppp1r1b | P | Pons | 52.09 | |
| 56.62 | | |||
| Ppp1r1b | PAL | Pallidum | 72.99 | |
| 93.29 | | |||
| Ppp1r1b | RHP | Retrohippocampal region | 92.81 | |
| 100 | | |||
| Ppp1r1b | sAMY | Striatum-like amygdalar nuclei | 77.8 | |
| 90.12 | | |||
| Ppp1r1b | STR | Striatum | 100 | |
| 100 | | |||
| Ppp1r1b | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Ppp1r1b | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Ppp1r1b | TH | Thalamus | 59.09 | |
| 59.07 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00076814 | 13 | 68 | 80 | RPNPCAYTPPSLK | Peptide Atlas |