AutismKB 2.0

Annotation Detail for KIAA1109


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Basic Information Top
Gene Symbol:KIAA1109 ( DKFZp781P0474,FSA,MGC110967 )
Gene Full Name: KIAA1109
Band: 4q27
Quick LinksEntrez ID:84162; OMIM: 611565; Uniprot ID:K1109_HUMAN; ENSEMBL ID: ENSG00000138688; HGNC ID: 26953
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus29 / 56401251
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult129 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal219 / 336030765
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone5 / 7165569
bone marrow2 / 4880140
brain89 / 110098980
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye19 / 21105490
heart3 / 8962633
intestine6 / 23447225
kidney3 / 21177714
larynx0 / 241450 
liver5 / 20774324
lung8 / 33697423
lymph0 / 442700 
lymph node8 / 9161087
mammary gland15 / 15327197
mouth1 / 6705214
muscle16 / 107715148
nerve1 / 1576863
ovary0 / 1020510 
pancreas14 / 21481265
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta20 / 28082571
prostate9 / 18934547
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach3 / 9661931
testis9 / 33044227
thymus7 / 8113186
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212779_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.6
Adipocyte29
AdrenalCortex44.2
Adrenalgland23.15
Amygdala385.45
Appendix50.85
AtrioventricularNode56.65
BDCA4+_DentriticCells40.35
Bonemarrow27.6
BronchialEpithelialCells25.35
CD105+_Endothelial31.45
CD14+_Monocytes56.6
CD19+_BCells(neg._sel.)54.15
CD33+_Myeloid121.75
CD34+68.65
CD4+_Tcells255.65
CD56+_NKCells93.2
CD71+_EarlyErythroid16.9
CD8+_Tcells234.15
CardiacMyocytes29
Caudatenucleus97.25
Cerebellum25.6
CerebellumPeduncles67.4
CiliaryGanglion27.8
CingulateCortex135.55
Colorectaladenocarcinoma26.65
DorsalRootGanglion37.95
FetalThyroid49.65
Fetalbrain248.5
Fetalliver29.85
Fetallung81
GlobusPallidus57.6
Heart37.25
Hypothalamus241.2
Kidney22.8
Leukemia_chronicMyelogenousK-56225.85
Leukemia_promyelocytic-HL-6025.55
Leukemialymphoblastic(MOLT-4)31.9
Liver32.3
Lung19.8
Lymphnode99.9
Lymphoma_burkitts(Daudi)43.7
Lymphoma_burkitts(Raji)48.45
MedullaOblongata125.8
OccipitalLobe129.4
OlfactoryBulb100
Ovary37.95
Pancreas33.05
PancreaticIslet39.25
ParietalLobe57.4
Pituitary114
Placenta24.8
Pons49.55
PrefrontalCortex360.25
Prostate38.45
Salivarygland37
SkeletalMuscle30.5
Skin38.7
SmoothMuscle34.45
Spinalcord158.45
SubthalamicNucleus55.9
SuperiorCervicalGanglion67.25
TemporalLobe74.2
Testis25.05
TestisGermCell51.15
TestisIntersitial41.9
TestisLeydigCell50.45
TestisSeminiferousTubule37.1
Thalamus115.85
Thymus18.75
Thyroid166.9
Tongue44.3
Tonsil34.05
Trachea25.1
TrigeminalGanglion47.55
Uterus152.6
UterusCorpus30.4
WholeBlood104.05
Wholebrain33.35
colon44.55
pineal_day377.32
pineal_night309.7
retina70.65
small_intestine32.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P147869
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.52 ± 0.16
Basal Forebrain10.62 ± 0.18
Basal Part of Pons10.3 ± 0.16
Cerebellar Cortex10.35 ± 0.17
Cerebellar Nuclei10.44 ± 0.19
Claustrum10.78 ± 0.26
Epithalamus10.24 ± 0.33
Frontal Lobe10.41 ± 0.19
Globus Pallidus10.68 ± 0.08
Hypothalamus10.29 ± 0.17
Insula10.37 ± 0.14
Limbic Lobe10.49 ± 0.23
Mesencephalon10.5 ± 0.21
Myelencephalon10.48 ± 0.24
Occipital Lobe10.76 ± 0.29
Parietal Lobe10.5 ± 0.18
Pontine Tegmentum10.51 ± 0.22
Striatum10.7 ± 0.18
Subthalamus10.64 ± 0.08
Temporal Lobe10.41 ± 0.19
Thalamus10.6 ± 0.19
White Matter11.1 ± 0.24
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00490227 11 771 781 LSLSTSSSSGW Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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