AutismKB 2.0

Annotation Detail for TMEM117


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Basic Information Top
Gene Symbol:TMEM117 ( DKFZp434K2435 )
Gene Full Name: transmembrane protein 117
Band: 12q12
Quick LinksEntrez ID:84216; OMIM: NA; Uniprot ID:TM117_HUMAN; ENSEMBL ID: ENSG00000139173; HGNC ID: 25308
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal46 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain30 / 110098927
cervix1 / 4817120
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth2 / 6705229
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7080_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.06 ± 0.68
Basal Forebrain3.52 ± 0.52
Basal Part of Pons4.51 ± 0.32
Cerebellar Cortex3.87 ± 0.42
Cerebellar Nuclei4.43 ± 0.7
Claustrum3.71 ± 0.5
Epithalamus3.75 ± 0.66
Frontal Lobe3.87 ± 0.52
Globus Pallidus4.09 ± 0.7
Hypothalamus3.85 ± 0.51
Insula3.96 ± 0.51
Limbic Lobe3.82 ± 0.62
Mesencephalon3.93 ± 0.55
Myelencephalon3.79 ± 0.58
Occipital Lobe3.87 ± 0.58
Parietal Lobe3.88 ± 0.55
Pontine Tegmentum3.7 ± 0.59
Striatum3.62 ± 0.85
Subthalamus4.04 ± 0.37
Temporal Lobe3.77 ± 0.52
Thalamus3.76 ± 0.71
White Matter5.39 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem117CBCerebellum0.89
1.15
Tmem117CTXCerebral cortex0.89
0.82
Tmem117HIPHippocampal region0.88
0.77
Tmem117HPFHippocampal formation1.27
1
Tmem117HYHypothalamus0.02
0.03
Tmem117LSXLateral septal complex0.26
0.9
Tmem117MBMidbrain0.26
0.58
Tmem117MYMedulla0.93
1.44
Tmem117OLFOlfactory bulb2.53
2.24
Tmem117PPons1.2
1.37
Tmem117PALPallidum0.13
0.22
Tmem117RHPRetrohippocampal region2.18
1.48
Tmem117sAMYStriatum-like amygdalar nuclei0.16
0.77
Tmem117STRStriatum0.37
0.41
Tmem117STRdStriatum dorsal region0.5
0.41
Tmem117STRvStriatum ventral region0.22
0.17
Tmem117THThalamus0.15
0.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018