AutismKB 2.0

Annotation Detail for TRAF7


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Basic Information Top
Gene Symbol:TRAF7 ( DKFZp586I021,MGC7807,RFWD1,RNF119 )
Gene Full Name: TNF receptor-associated factor 7
Band: 16p13.3
Quick LinksEntrez ID:84231; OMIM: 606692; Uniprot ID:TRAF7_HUMAN; ENSEMBL ID: ENSG00000131653; HGNC ID: 20456
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst5 / 6231980
fetus36 / 56401263
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult175 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor16 / 94178169
cervical tumor1 / 3436629
chondrosarcoma22 / 82823265
colorectal tumor13 / 114246113
esophageal tumor1 / 1729057
gastrointestinal tumor14 / 119369117
germ cell tumor13 / 26384549
glioma26 / 106883243
head and neck tumor8 / 13630258
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor9 / 9635993
lung tumor26 / 103127252
lymphoma42 / 71755585
non-neoplasia2 / 9725020
normal174 / 336030751
ovarian tumor17 / 76682221
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer28 / 102680272
retinoblastoma7 / 46356151
skin tumor11 / 12494988
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites6 / 40015149
bladder1 / 2975733
blood7 / 12347856
bone13 / 71655181
bone marrow5 / 48801102
brain67 / 110098960
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus1 / 2020949
eye26 / 211054123
heart4 / 8962644
intestine25 / 234472106
kidney7 / 21177733
larynx0 / 241450 
liver10 / 20774348
lung54 / 336974160
lymph42 / 44270948
lymph node6 / 9161065
mammary gland16 / 153271104
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary18 / 102051176
pancreas22 / 214812102
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta12 / 28082542
prostate33 / 189345174
salivary gland2 / 2015599
skin18 / 21057485
spleen2 / 5395237
stomach7 / 9661972
testis8 / 33044224
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P206474
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.1 ± 0.48
Basal Forebrain4.12 ± 0.22
Basal Part of Pons4.01 ± 0.45
Cerebellar Cortex4.05 ± 0.37
Cerebellar Nuclei3.33 ± 0.37
Claustrum4.02 ± 0.68
Epithalamus4.1 ± 0.56
Frontal Lobe4.06 ± 0.48
Globus Pallidus3.64 ± 0.77
Hypothalamus3.73 ± 0.54
Insula4.17 ± 0.61
Limbic Lobe4.44 ± 0.4
Mesencephalon4.06 ± 0.51
Myelencephalon4.14 ± 0.5
Occipital Lobe4.4 ± 0.43
Parietal Lobe4.25 ± 0.37
Pontine Tegmentum4.08 ± 0.49
Striatum4.13 ± 0.51
Subthalamus3.92 ± 0.4
Temporal Lobe4.13 ± 0.46
Thalamus4 ± 0.46
White Matter2.88 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Traf7CBCerebellum41.38
32.48
Traf7CTXCerebral cortex51.35
38.65
Traf7HIPHippocampal region46.71
43.92
Traf7HPFHippocampal formation56.38
47.29
Traf7HYHypothalamus51.06
25.05
Traf7LSXLateral septal complex50.07
41.45
Traf7MBMidbrain50.41
31.76
Traf7MYMedulla49.6
40.88
Traf7OLFOlfactory bulb54.49
42.68
Traf7PPons53
47.76
Traf7PALPallidum50.38
29.46
Traf7RHPRetrohippocampal region52.51
49.5
Traf7sAMYStriatum-like amygdalar nuclei51.16
24.57
Traf7STRStriatum50.45
24.23
Traf7STRdStriatum dorsal region42.39
18
Traf7STRvStriatum ventral region50.48
38.12
Traf7THThalamus29.66
15.2
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018