AutismKB 2.0

Annotation Detail for LDOC1L


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Basic Information Top
Gene Symbol:LDOC1L ( DKFZp761O17121,Mar6,Mart6,dJ1033E15.2 )
Gene Full Name: leucine zipper, down-regulated in cancer 1-like
Band: 22q13.31
Quick LinksEntrez ID:84247; OMIM: NA; Uniprot ID:LDOCL_HUMAN; ENSEMBL ID: ENSG00000188636; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst7 / 62319112
fetus40 / 56401270
neonate1 / 3109732
infant1 / 2362042
juvenile3 / 5555653
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor7 / 68959101
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal163 / 336030748
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone6 / 7165583
bone marrow2 / 4880140
brain98 / 110098989
cervix1 / 4817120
connective tissue1 / 1492556
ear3 / 16212185
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine6 / 23447225
kidney10 / 21177747
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph0 / 442700 
lymph node1 / 9161010
mammary gland9 / 15327158
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach0 / 966190 
testis15 / 33044245
thymus6 / 8113173
thyroid2 / 4747342
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P96474
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.64 ± 0.26
Basal Forebrain7.85 ± 0.17
Basal Part of Pons7.89 ± 0.34
Cerebellar Cortex7.81 ± 0.23
Cerebellar Nuclei7.53 ± 0.35
Claustrum7.53 ± 0.57
Epithalamus7.75 ± 0.22
Frontal Lobe7.87 ± 0.29
Globus Pallidus7.57 ± 0.21
Hypothalamus7.85 ± 0.37
Insula7.98 ± 0.3
Limbic Lobe7.62 ± 0.42
Mesencephalon7.76 ± 0.4
Myelencephalon7.7 ± 0.38
Occipital Lobe7.38 ± 0.47
Parietal Lobe7.75 ± 0.31
Pontine Tegmentum7.66 ± 0.32
Striatum7.2 ± 0.28
Subthalamus7.73 ± 0.18
Temporal Lobe7.92 ± 0.29
Thalamus7.67 ± 0.29
White Matter7.2 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ldoc1lCBCerebellum10.66
12.97
Ldoc1lCTXCerebral cortex30.02
20.27
Ldoc1lHIPHippocampal region19.82
20.55
Ldoc1lHPFHippocampal formation19.52
17.8
Ldoc1lHYHypothalamus6.01
4.27
Ldoc1lLSXLateral septal complex11.19
7.74
Ldoc1lMBMidbrain7.99
7.18
Ldoc1lMYMedulla4.89
5.06
Ldoc1lOLFOlfactory bulb31.16
23.55
Ldoc1lPPons6.31
5.52
Ldoc1lPALPallidum6.48
5.06
Ldoc1lRHPRetrohippocampal region19.24
14.1
Ldoc1lsAMYStriatum-like amygdalar nuclei14.04
9.59
Ldoc1lSTRStriatum12.98
8.69
Ldoc1lSTRdStriatum dorsal region13.11
8.82
Ldoc1lSTRvStriatum ventral region12.23
7.83
Ldoc1lTHThalamus12.01
9.24
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018