AutismKB 2.0

Annotation Detail for FBXW9


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Basic Information Top
Gene Symbol:FBXW9 ( Fbw9,MGC10870 )
Gene Full Name: F-box and WD repeat domain containing 9
Band: 19p13.13
Quick LinksEntrez ID:84261; OMIM: 609074; Uniprot ID:FBXW9_HUMAN; ENSEMBL ID: ENSG00000132004; HGNC ID: 28136
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma5 / 7175569
non-neoplasia3 / 9725030
normal66 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood2 / 12347816
bone5 / 7165569
bone marrow0 / 488010 
brain24 / 110098921
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung9 / 33697426
lymph4 / 4427090
lymph node2 / 9161021
mammary gland8 / 15327152
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate11 / 18934558
salivary gland10 / 20155496
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5407_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.92 ± 0.76
Basal Forebrain3.3 ± 0.42
Basal Part of Pons3.98 ± 0.79
Cerebellar Cortex3.85 ± 0.66
Cerebellar Nuclei3.58 ± 0.84
Claustrum3.32 ± 0.71
Epithalamus4.75 ± 1.1
Frontal Lobe4.09 ± 0.56
Globus Pallidus3.03 ± 0.65
Hypothalamus3.82 ± 0.68
Insula4.23 ± 0.43
Limbic Lobe3.75 ± 0.69
Mesencephalon3.83 ± 0.69
Myelencephalon3.79 ± 0.72
Occipital Lobe3.09 ± 0.78
Parietal Lobe3.76 ± 0.58
Pontine Tegmentum3.75 ± 0.67
Striatum3.05 ± 0.83
Subthalamus4.25 ± 0.49
Temporal Lobe4.14 ± 0.54
Thalamus3.71 ± 0.57
White Matter2.65 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxw9CBCerebellum3.63
3.67
Fbxw9CTXCerebral cortex8.68
5.76
Fbxw9HIPHippocampal region2.42
2.06
Fbxw9HPFHippocampal formation2.21
2.03
Fbxw9HYHypothalamus0.4
0.32
Fbxw9LSXLateral septal complex1.42
1.04
Fbxw9MBMidbrain0.8
0.81
Fbxw9MYMedulla4.15
3.87
Fbxw9OLFOlfactory bulb13.32
9.18
Fbxw9PPons2.22
2.17
Fbxw9PALPallidum2.47
1.99
Fbxw9RHPRetrohippocampal region1.9
1.94
Fbxw9sAMYStriatum-like amygdalar nuclei2.99
2.28
Fbxw9STRStriatum2.7
1.89
Fbxw9STRdStriatum dorsal region2.39
1.75
Fbxw9STRvStriatum ventral region4.2
2.58
Fbxw9THThalamus1.8
1.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FBXW9_HUMAN_98 8 98 105 LVLHVLSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018