AutismKB 2.0

Annotation Detail for HAGHL


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Basic Information Top
Gene Symbol:HAGHL ( MGC2605 )
Gene Full Name: hydroxyacylglutathione hydrolase-like
Band: 16p13.3
Quick LinksEntrez ID:84264; OMIM: NA; Uniprot ID:HAGHL_HUMAN; ENSEMBL ID: ENSG00000103253; HGNC ID: 14177
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma6 / 7175583
non-neoplasia0 / 972500 
normal46 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain34 / 110098930
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph6 / 44270135
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6446_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.49 ± 0.88
Basal Forebrain3.15 ± 0.47
Basal Part of Pons3.9 ± 0.71
Cerebellar Cortex3.45 ± 0.71
Cerebellar Nuclei3.38 ± 0.71
Claustrum3.02 ± 0.85
Epithalamus4.18 ± 0.95
Frontal Lobe3.68 ± 0.64
Globus Pallidus3.4 ± 0.42
Hypothalamus3.2 ± 0.46
Insula3.48 ± 0.51
Limbic Lobe3.25 ± 0.65
Mesencephalon3.47 ± 0.62
Myelencephalon3.47 ± 0.62
Occipital Lobe3.06 ± 0.6
Parietal Lobe3.6 ± 0.61
Pontine Tegmentum3.48 ± 0.72
Striatum3.82 ± 0.56
Subthalamus3.79 ± 0.36
Temporal Lobe3.49 ± 0.65
Thalamus3.53 ± 0.62
White Matter3.38 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HaghlCBCerebellum44.03
99.36
HaghlCTXCerebral cortex100
97.19
HaghlHIPHippocampal region71.8
82.2
HaghlHPFHippocampal formation97.19
90.97
HaghlHYHypothalamus100
93.54
HaghlLSXLateral septal complex100
60.64
HaghlMBMidbrain100
100
HaghlMYMedulla100
100
HaghlOLFOlfactory bulb100
84.4
HaghlPPons100
100
HaghlPALPallidum100
97.53
HaghlRHPRetrohippocampal region100
100
HaghlsAMYStriatum-like amygdalar nuclei100
78.59
HaghlSTRStriatum100
64.7
HaghlSTRdStriatum dorsal region100
69.61
HaghlSTRvStriatum ventral region98.18
47.46
HaghlTHThalamus100
93.85
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018