AutismKB 2.0

Annotation Detail for CARD11


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Basic Information Top
Gene Symbol:CARD11 ( BIMP3,CARMA1,MGC133069 )
Gene Full Name: caspase recruitment domain family, member 11
Band: 7p22.2
Quick LinksEntrez ID:84433; OMIM: 607210; Uniprot ID:CAR11_HUMAN; ENSEMBL ID: ENSG00000198286; HGNC ID: 16393
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia9 / 9584293
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma22 / 71755306
non-neoplasia0 / 972500 
normal49 / 336030714
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung0 / 3369740 
lymph18 / 44270406
lymph node20 / 91610218
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta3 / 28082510
prostate8 / 18934542
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus6 / 8113173
thyroid0 / 474730 
tonsil7 / 16999411
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10242_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.07 ± 0.96
Basal Forebrain1.59 ± 0.17
Basal Part of Pons1.67 ± 0.59
Cerebellar Cortex1.7 ± 0.76
Cerebellar Nuclei2.02 ± 0.72
Claustrum2.69 ± 0.94
Epithalamus1.47 ± 0.71
Frontal Lobe1.79 ± 0.67
Globus Pallidus2.31 ± 0.29
Hypothalamus1.8 ± 0.7
Insula1.79 ± 0.53
Limbic Lobe1.72 ± 0.71
Mesencephalon1.95 ± 0.68
Myelencephalon1.93 ± 0.62
Occipital Lobe1.87 ± 0.71
Parietal Lobe1.79 ± 0.79
Pontine Tegmentum1.9 ± 0.76
Striatum1.92 ± 0.57
Subthalamus1.85 ± 0.63
Temporal Lobe1.76 ± 0.63
Thalamus2.47 ± 0.66
White Matter2.58 ± 0.81
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Card11CBCerebellum0.27
0.53
Card11CTXCerebral cortex0.26
0.33
Card11HIPHippocampal region0.13
0.21
Card11HPFHippocampal formation0.2
0.31
Card11HYHypothalamus0.22
0.5
Card11LSXLateral septal complex0.06
0.07
Card11MBMidbrain0.12
0.33
Card11MYMedulla0.35
0.91
Card11OLFOlfactory bulb0.24
0.36
Card11PPons0.22
0.33
Card11PALPallidum0.19
0.26
Card11RHPRetrohippocampal region0.35
0.53
Card11sAMYStriatum-like amygdalar nuclei0.11
0.15
Card11STRStriatum0.14
0.13
Card11STRdStriatum dorsal region0.15
0.14
Card11STRvStriatum ventral region0.14
0.13
Card11THThalamus0.07
0.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CAR11_HUMAN_0 1 0 0 NQELQSIIQAGKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018