AutismKB 2.0

Annotation Detail for DUSP11


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Basic Information Top
Gene Symbol:DUSP11 ( PIR1 )
Gene Full Name: dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Band: 2p13.1
Quick LinksEntrez ID:8446; OMIM: 603092; Uniprot ID:DUS11_HUMAN; ENSEMBL ID: ENSG00000144048; HGNC ID: 3066
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus35 / 56401262
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor13 / 17290751
gastrointestinal tumor7 / 11936958
germ cell tumor8 / 26384530
glioma9 / 10688384
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal130 / 336030738
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites5 / 40015124
bladder2 / 2975767
blood4 / 12347832
bone4 / 7165555
bone marrow8 / 48801163
brain28 / 110098925
cervix5 / 48171103
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus13 / 20209643
eye5 / 21105423
heart1 / 8962611
intestine11 / 23447246
kidney16 / 21177775
larynx3 / 24145124
liver3 / 20774314
lung13 / 33697438
lymph0 / 442700 
lymph node6 / 9161065
mammary gland10 / 15327165
mouth1 / 6705214
muscle7 / 10771564
nerve0 / 157680 
ovary5 / 10205148
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx11 / 41328266
pituitary gland1 / 1658560
placenta8 / 28082528
prostate7 / 18934536
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach3 / 9661931
testis7 / 33044221
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus21 / 23287890
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202703_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.4
Adipocyte9.2
AdrenalCortex11
Adrenalgland9.55
Amygdala13
Appendix15.55
AtrioventricularNode8.6
BDCA4+_DentriticCells23.15
Bonemarrow16.15
BronchialEpithelialCells49.7
CD105+_Endothelial13.35
CD14+_Monocytes17.55
CD19+_BCells(neg._sel.)24.2
CD33+_Myeloid15.45
CD34+25.1
CD4+_Tcells25
CD56+_NKCells32.8
CD71+_EarlyErythroid9.35
CD8+_Tcells25.25
CardiacMyocytes16.05
Caudatenucleus8.95
Cerebellum9.8
CerebellumPeduncles14.6
CiliaryGanglion6.25
CingulateCortex11.1
Colorectaladenocarcinoma16.4
DorsalRootGanglion13.3
FetalThyroid10.1
Fetalbrain12.4
Fetalliver11.5
Fetallung11.95
GlobusPallidus6.8
Heart10.35
Hypothalamus12.9
Kidney10.2
Leukemia_chronicMyelogenousK-56212.75
Leukemia_promyelocytic-HL-6015.75
Leukemialymphoblastic(MOLT-4)12.7
Liver12.35
Lung19.1
Lymphnode17.85
Lymphoma_burkitts(Daudi)35.55
Lymphoma_burkitts(Raji)16.25
MedullaOblongata9.9
OccipitalLobe8.9
OlfactoryBulb11.4
Ovary8.2
Pancreas8.8
PancreaticIslet10.75
ParietalLobe11.9
Pituitary15.7
Placenta18.1
Pons11.95
PrefrontalCortex17.45
Prostate23.7
Salivarygland10.5
SkeletalMuscle12.05
Skin9
SmoothMuscle16.3
Spinalcord8.25
SubthalamicNucleus10.15
SuperiorCervicalGanglion21.4
TemporalLobe11.2
Testis27.85
TestisGermCell25.3
TestisIntersitial15.95
TestisLeydigCell13.4
TestisSeminiferousTubule16.45
Thalamus8.15
Thymus23.65
Thyroid17.2
Tongue13.35
Tonsil18.35
Trachea12.4
TrigeminalGanglion13.25
Uterus23
UterusCorpus11.7
WholeBlood53.85
Wholebrain11.75
colon17.8
pineal_day14.58
pineal_night17.06
retina15.4
small_intestine40.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13221_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.1 ± 0.35
Basal Forebrain5.95 ± 0.14
Basal Part of Pons5.78 ± 0.4
Cerebellar Cortex6.12 ± 0.23
Cerebellar Nuclei5.58 ± 0.33
Claustrum6.07 ± 0.36
Epithalamus5.72 ± 0.38
Frontal Lobe5.74 ± 0.35
Globus Pallidus5.53 ± 0.3
Hypothalamus5.64 ± 0.28
Insula5.7 ± 0.2
Limbic Lobe5.89 ± 0.36
Mesencephalon5.92 ± 0.34
Myelencephalon5.79 ± 0.34
Occipital Lobe6.15 ± 0.3
Parietal Lobe5.91 ± 0.31
Pontine Tegmentum5.86 ± 0.38
Striatum5.71 ± 0.3
Subthalamus5.76 ± 0.33
Temporal Lobe5.81 ± 0.33
Thalamus5.73 ± 0.28
White Matter6.3 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dusp11CBCerebellum63.77
83.21
Dusp11CTXCerebral cortex100
93.12
Dusp11HIPHippocampal region78.77
100
Dusp11HPFHippocampal formation89.55
100
Dusp11HYHypothalamus100
83.23
Dusp11LSXLateral septal complex99.7
68.28
Dusp11MBMidbrain88.68
76.96
Dusp11MYMedulla83.09
77.97
Dusp11OLFOlfactory bulb100
95.17
Dusp11PPons81.37
74.33
Dusp11PALPallidum83.43
69.11
Dusp11RHPRetrohippocampal region100
89.48
Dusp11sAMYStriatum-like amygdalar nuclei100
82.02
Dusp11STRStriatum100
91.6
Dusp11STRdStriatum dorsal region100
96.11
Dusp11STRvStriatum ventral region100
91.59
Dusp11THThalamus95.98
81.47
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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