Annotation Detail for SLX4
Basic Information Top
| Gene Symbol: | SLX4 ( BTBD12,KIAA1784,KIAA1987,MUS312 ) |
|---|---|
| Gene Full Name: | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:84464; OMIM: 613278; Uniprot ID:SLX4_HUMAN; ENSEMBL ID: ENSG00000188827; HGNC ID: 23845 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.143681
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 8 / 564012 | 14 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 12 / 1939121 | 6 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 32 / 3360307 | 9 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 9 / 1100989 | 8 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 3 / 336974 | 8 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 10 / 91610 | 109 |  |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 4 / 330442 | 12 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_8327_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.83 ± 0.68 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.73 ± 0.36 | |
| Basal Part of Pons | 3.22 ± 0.69 | |
| Cerebellar Cortex | 3.5 ± 0.54 | |
| Cerebellar Nuclei | 3.73 ± 0.9 | |
| Claustrum | 4.22 ± 0.95 | |
| Epithalamus | 2.67 ± 0.54 | |
| Frontal Lobe | 3.43 ± 0.73 | |
| Globus Pallidus | 4.03 ± 0.81 | |
| Hypothalamus | 3.38 ± 0.64 | |
| Insula | 3.35 ± 0.44 | |
| Limbic Lobe | 3.7 ± 0.72 | |
| Mesencephalon | 3.66 ± 0.75 | |
| Myelencephalon | 3.62 ± 0.75 | |
| Occipital Lobe | 3.82 ± 0.74 | |
| Parietal Lobe | 3.62 ± 0.78 | |
| Pontine Tegmentum | 3.65 ± 0.73 | |
| Striatum | 3.88 ± 0.83 | |
| Subthalamus | 2.98 ± 1.1 | |
| Temporal Lobe | 3.53 ± 0.73 | |
| Thalamus | 3.75 ± 0.6 | |
| White Matter | 3.02 ± 1.1 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Btbd12 | CB | Cerebellum | 9.09 | |
| 8.76 | | |||
| Btbd12 | CTX | Cerebral cortex | 42.62 | |
| 29.27 | | |||
| Btbd12 | HIP | Hippocampal region | 24.48 | |
| 23.24 | | |||
| Btbd12 | HPF | Hippocampal formation | 27.41 | |
| 23.35 | | |||
| Btbd12 | HY | Hypothalamus | 18.17 | |
| 12.29 | | |||
| Btbd12 | LSX | Lateral septal complex | 3.79 | |
| 2.4 | | |||
| Btbd12 | MB | Midbrain | 15.54 | |
| 11.89 | | |||
| Btbd12 | MY | Medulla | 22.49 | |
| 19.95 | | |||
| Btbd12 | OLF | Olfactory bulb | 35.16 | |
| 26.2 | | |||
| Btbd12 | P | Pons | 19.35 | |
| 15.65 | | |||
| Btbd12 | PAL | Pallidum | 19.5 | |
| 15.01 | | |||
| Btbd12 | RHP | Retrohippocampal region | 33 | |
| 24.12 | | |||
| Btbd12 | sAMY | Striatum-like amygdalar nuclei | 25.03 | |
| 16.28 | | |||
| Btbd12 | STR | Striatum | 17.42 | |
| 11.55 | | |||
| Btbd12 | STRd | Striatum dorsal region | 16.27 | |
| 10.98 | | |||
| Btbd12 | STRv | Striatum ventral region | 23.81 | |
| 14.9 | | |||
| Btbd12 | TH | Thalamus | 20.35 | |
| 14.61 | |