Annotation Detail for MCM8
Basic Information Top
| Gene Symbol: | MCM8 ( C20orf154,MGC119522,MGC119523,MGC12866,MGC4816,REC,dJ967N21.5 ) |
|---|---|
| Gene Full Name: | minichromosome maintenance complex component 8 |
| Band: | 20p12.3 |
| Quick Links | Entrez ID:84515; OMIM: 608187; Uniprot ID:MCM8_HUMAN; ENSEMBL ID: ENSG00000125885; HGNC ID: 16147 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.597484
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 6 / 70761 | 84 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 7 / 564012 | 12 | |
| neonate | 2 / 31097 | 64 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 51 / 1939121 | 26 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 40 / 3360307 | 11 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 15 / 124949 | 120 | |
| soft tissue/muscle tissue tumor | 12 / 125191 | 95 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 8 / 1100989 | 7 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 4 / 89626 | 44 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 1 / 24145 | 41 | |
| liver | 6 / 207743 | 28 | |
| lung | 2 / 336974 | 5 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 17 / 210574 | 80 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 17 / 330442 | 51 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: A_24_P305556
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.84 ± 1.42 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.07 ± 0.26 | |
| Basal Part of Pons | 3.2 ± 0.48 | |
| Cerebellar Cortex | 4.15 ± 0.23 | |
| Cerebellar Nuclei | 3.6 ± 0.61 | |
| Claustrum | 3.79 ± 0.71 | |
| Epithalamus | 3.81 ± 0.67 | |
| Frontal Lobe | 3.45 ± 0.63 | |
| Globus Pallidus | 3.78 ± 0.72 | |
| Hypothalamus | 3.33 ± 0.51 | |
| Insula | 3.33 ± 0.62 | |
| Limbic Lobe | 3.31 ± 0.58 | |
| Mesencephalon | 3.66 ± 0.6 | |
| Myelencephalon | 3.57 ± 0.56 | |
| Occipital Lobe | 3.86 ± 0.63 | |
| Parietal Lobe | 3.47 ± 0.63 | |
| Pontine Tegmentum | 3.5 ± 0.74 | |
| Striatum | 3.25 ± 0.7 | |
| Subthalamus | 3.75 ± 0.11 | |
| Temporal Lobe | 3.5 ± 0.67 | |
| Thalamus | 3.55 ± 0.58 | |
| White Matter | 5.04 ± 0.09 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Mcm8 | CB | Cerebellum | 0.58 | |
| 0.82 | | |||
| Mcm8 | CTX | Cerebral cortex | 0.39 | |
| 0.39 | | |||
| Mcm8 | HIP | Hippocampal region | 0.21 | |
| 0.29 | | |||
| Mcm8 | HPF | Hippocampal formation | 0.17 | |
| 0.22 | | |||
| Mcm8 | HY | Hypothalamus | 0.49 | |
| 0.36 | | |||
| Mcm8 | LSX | Lateral septal complex | 0.07 | |
| 0.06 | | |||
| Mcm8 | MB | Midbrain | 0.38 | |
| 0.6 | | |||
| Mcm8 | MY | Medulla | 1.68 | |
| 2.03 | | |||
| Mcm8 | OLF | Olfactory bulb | 0.81 | |
| 1.01 | | |||
| Mcm8 | P | Pons | 0.86 | |
| 0.99 | | |||
| Mcm8 | PAL | Pallidum | 0.13 | |
| 0.1 | | |||
| Mcm8 | RHP | Retrohippocampal region | 0.12 | |
| 0.13 | | |||
| Mcm8 | sAMY | Striatum-like amygdalar nuclei | 0.12 | |
| 0.13 | | |||
| Mcm8 | STR | Striatum | 0.11 | |
| 0.18 | | |||
| Mcm8 | STRd | Striatum dorsal region | 0.11 | |
| 0.21 | | |||
| Mcm8 | STRv | Striatum ventral region | 0.13 | |
| 0.15 | | |||
| Mcm8 | TH | Thalamus | 0.43 | |
| 0.45 | |