AutismKB 2.0

Annotation Detail for HOPX


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Basic Information Top
Gene Symbol:HOPX ( CAMEO,HOD,HOP,LAGY,MGC20820,NECC1,OB1,SMAP31,TOTO )
Gene Full Name: HOP homeobox
Band: 4q12
Quick LinksEntrez ID:84525; OMIM: 607275; Uniprot ID:HOP_HUMAN; ENSEMBL ID: ENSG00000171476; HGNC ID: 24961
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst6 / 6231996
fetus21 / 56401237
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult173 / 193912189
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor5 / 26384518
glioma9 / 10688384
head and neck tumor34 / 136302249
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal260 / 336030777
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor35 / 125191279
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone0 / 716550 
bone marrow7 / 48801143
brain140 / 1100989127
cervix0 / 481710 
connective tissue35 / 149255234
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye6 / 21105428
heart3 / 8962633
intestine7 / 23447229
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung30 / 33697489
lymph0 / 442700 
lymph node13 / 91610141
mammary gland1 / 1532716
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta27 / 28082596
prostate7 / 18934536
salivary gland0 / 201550 
skin50 / 210574237
spleen0 / 539520 
stomach13 / 96619134
testis19 / 33044257
thymus0 / 811310 
thyroid34 / 47473716
tonsil4 / 16999235
trachea1 / 5241319
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211597_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte7.95
AdrenalCortex46.8
Adrenalgland35.1
Amygdala1185.6
Appendix17.6
AtrioventricularNode6.75
BDCA4+_DentriticCells7.45
Bonemarrow15.35
BronchialEpithelialCells19.2
CD105+_Endothelial6.5
CD14+_Monocytes8.15
CD19+_BCells(neg._sel.)340.6
CD33+_Myeloid6.15
CD34+197.5
CD4+_Tcells136.85
CD56+_NKCells2630.55
CD71+_EarlyErythroid7.35
CD8+_Tcells372.05
CardiacMyocytes13
Caudatenucleus51.85
Cerebellum105.9
CerebellumPeduncles76.5
CiliaryGanglion6
CingulateCortex445.85
Colorectaladenocarcinoma6.5
DorsalRootGanglion6.65
FetalThyroid610.6
Fetalbrain305.9
Fetalliver7.05
Fetallung928.1
GlobusPallidus258.8
Heart10.35
Hypothalamus71.15
Kidney6.7
Leukemia_chronicMyelogenousK-5627.35
Leukemia_promyelocytic-HL-607.1
Leukemialymphoblastic(MOLT-4)6.2
Liver18.7
Lung1839.35
Lymphnode28.1
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)11.4
MedullaOblongata305.6
OccipitalLobe712.25
OlfactoryBulb47.7
Ovary6.15
Pancreas6.15
PancreaticIslet612.6
ParietalLobe295.65
Pituitary17.7
Placenta2725.35
Pons193.95
PrefrontalCortex762.8
Prostate22.65
Salivarygland13.05
SkeletalMuscle9.9
Skin1050.3
SmoothMuscle9.25
Spinalcord284.4
SubthalamicNucleus440.5
SuperiorCervicalGanglion26.95
TemporalLobe615.9
Testis340.7
TestisGermCell330.5
TestisIntersitial38.85
TestisLeydigCell206.45
TestisSeminiferousTubule107.15
Thalamus37
Thymus15.3
Thyroid1354
Tongue2442.15
Tonsil901.95
Trachea12.35
TrigeminalGanglion12.2
Uterus34.4
UterusCorpus8.1
WholeBlood214.2
Wholebrain1744.75
colon19.95
pineal_day39.14
pineal_night98.86
retina54.125
small_intestine35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P913146
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.68 ± 0.59
Basal Forebrain7.87 ± 0.26
Basal Part of Pons8.77 ± 0.38
Cerebellar Cortex7.48 ± 0.38
Cerebellar Nuclei8.11 ± 0.42
Claustrum8.03 ± 0.48
Epithalamus6.74 ± 0.67
Frontal Lobe8.12 ± 0.74
Globus Pallidus7.49 ± 0.92
Hypothalamus7.42 ± 0.44
Insula8.21 ± 0.45
Limbic Lobe8.63 ± 0.97
Mesencephalon7.56 ± 0.63
Myelencephalon8.22 ± 0.79
Occipital Lobe8.16 ± 0.57
Parietal Lobe8.25 ± 0.72
Pontine Tegmentum7.94 ± 0.55
Striatum6.86 ± 1.13
Subthalamus7.43 ± 0.48
Temporal Lobe8.51 ± 0.61
Thalamus7.5 ± 0.44
White Matter5.98 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HodCBCerebellum13.66
15.74
HodCTXCerebral cortex1
1.09
HodHIPHippocampal region3.69
5.11
HodHPFHippocampal formation3.91
5.39
HodHYHypothalamus1.79
1.29
HodLSXLateral septal complex1.17
0.73
HodMBMidbrain1.43
1.07
HodMYMedulla5.54
4.53
HodOLFOlfactory bulb1.68
1.32
HodPPons3.07
2.68
HodPALPallidum0.88
0.65
HodRHPRetrohippocampal region4.26
5.69
HodsAMYStriatum-like amygdalar nuclei0.26
0.25
HodSTRStriatum0.84
0.56
HodSTRdStriatum dorsal region0.64
0.44
HodSTRvStriatum ventral region1.62
0.99
HodTHThalamus1.26
0.71
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00734858 10 60 69 RSEGLPSECR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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