Annotation Detail for CUL1
Basic Information Top
| Gene Symbol: | CUL1 ( MGC149834,MGC149835 ) |
|---|---|
| Gene Full Name: | cullin 1 |
| Band: | 7q36.1 |
| Quick Links | Entrez ID:8454; OMIM: 603134; Uniprot ID:CUL1_HUMAN; ENSEMBL ID: ENSG00000055130; HGNC ID: 2551 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.146806
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 12 / 70761 | 169 |  |
| blastocyst | 7 / 62319 | 112 | |
| fetus | 83 / 564012 | 147 | |
| neonate | 4 / 31097 | 128 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 10 / 55556 | 179 | |
| adult | 221 / 1939121 | 113 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 21 / 94178 | 222 |  |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 15 / 82823 | 181 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 17 / 119369 | 142 | |
| germ cell tumor | 49 / 263845 | 185 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 16 / 136302 | 117 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 14 / 95842 | 146 | |
| liver tumor | 13 / 96359 | 134 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 15 / 71755 | 209 | |
| non-neoplasia | 15 / 97250 | 154 | |
| normal | 373 / 3360307 | 111 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 16 / 104616 | 152 | |
| primitive neuroectodermal tumor of the CNS | 10 / 125680 | 79 | |
| prostate cancer | 8 / 102680 | 77 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 14 / 125191 | 111 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 5 / 33197 | 150 | |
| ascites | 10 / 40015 | 249 | |
| bladder | 3 / 29757 | 100 | |
| blood | 10 / 123478 | 80 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 115 / 1100989 | 104 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 24 / 149255 | 160 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 27 / 215722 | 125 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 15 / 211054 | 71 | |
| heart | 13 / 89626 | 145 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 1 / 24145 | 41 | |
| liver | 19 / 207743 | 91 | |
| lung | 26 / 336974 | 77 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 23 / 91610 | 251 | |
| mammary gland | 31 / 153271 | 202 | |
| mouth | 10 / 67052 | 149 | |
| muscle | 13 / 107715 | 120 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 20 / 214812 | 93 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 22 / 280825 | 78 | |
| prostate | 16 / 189345 | 84 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 15 / 210574 | 71 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 8 / 96619 | 82 | |
| testis | 178 / 330442 | 538 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 18 / 232878 | 77 | |
| vascular | 7 / 51780 | 135 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 207614_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 162.25 | |
| Adipocyte | 32.4 | |
| AdrenalCortex | 24.7 | |
| Adrenalgland | 15.4 | |
| Amygdala | 42.4 | |
| Appendix | 28.85 | |
| AtrioventricularNode | 18.6 | |
| BDCA4+_DentriticCells | 82.6 | |
| Bonemarrow | 21.65 | |
| BronchialEpithelialCells | 110.8 | |
| CD105+_Endothelial | 43.05 | |
| CD14+_Monocytes | 92.75 | |
| CD19+_BCells(neg._sel.) | 100.2 | |
| CD33+_Myeloid | 93.35 | |
| CD34+ | 106.8 | |
| CD4+_Tcells | 126.85 | |
| CD56+_NKCells | 82.8 | |
| CD71+_EarlyErythroid | 40.15 | |
| CD8+_Tcells | 174.55 | |
| CardiacMyocytes | 42.6 | |
| Caudatenucleus | 27.15 | |
| Cerebellum | 24.05 | |
| CerebellumPeduncles | 38.65 | |
| CiliaryGanglion | 23.95 | |
| CingulateCortex | 34.3 | |
| Colorectaladenocarcinoma | 78.55 | |
| DorsalRootGanglion | 17.4 | |
| FetalThyroid | 36.9 | |
| Fetalbrain | 37.7 | |
| Fetalliver | 27.45 | |
| Fetallung | 31.85 | |
| GlobusPallidus | 24.9 | |
| Heart | 37.6 | |
| Hypothalamus | 49.05 | |
| Kidney | 6.15 |  |
| Leukemia_chronicMyelogenousK-562 | 58.65 | |
| Leukemia_promyelocytic-HL-60 | 57.35 | |
| Leukemialymphoblastic(MOLT-4) | 40.8 | |
| Liver | 38.25 | |
| Lung | 26.45 | |
| Lymphnode | 31.1 | |
| Lymphoma_burkitts(Daudi) | 144 | |
| Lymphoma_burkitts(Raji) | 46.05 | |
| MedullaOblongata | 27.25 | |
| OccipitalLobe | 33.9 | |
| OlfactoryBulb | 19.85 | |
| Ovary | 28.15 | |
| Pancreas | 22.95 | |
| PancreaticIslet | 35.45 | |
| ParietalLobe | 40 | |
| Pituitary | 42.8 | |
| Placenta | 37.7 | |
| Pons | 33.4 | |
| PrefrontalCortex | 65 | |
| Prostate | 41.15 | |
| Salivarygland | 23.15 | |
| SkeletalMuscle | 27.4 | |
| Skin | 23.1 | |
| SmoothMuscle | 145.55 | |
| Spinalcord | 29.85 | |
| SubthalamicNucleus | 27.55 | |
| SuperiorCervicalGanglion | 32.35 | |
| TemporalLobe | 27 | |
| Testis | 60.25 | |
| TestisGermCell | 314.25 | |
| TestisIntersitial | 440.8 | |
| TestisLeydigCell | 194.55 | |
| TestisSeminiferousTubule | 158.65 | |
| Thalamus | 34.5 | |
| Thymus | 25.3 | |
| Thyroid | 37.8 | |
| Tongue | 28.45 | |
| Tonsil | 49.95 | |
| Trachea | 26.2 | |
| TrigeminalGanglion | 33.15 | |
| Uterus | 36.45 | |
| UterusCorpus | 24.1 | |
| WholeBlood | 42.75 | |
| Wholebrain | 42.9 | |
| colon | 36.5 | |
| pineal_day | 115.24 | |
| pineal_night | 86.06 | |
| retina | 39.1 | |
| small_intestine | 28.7 | |
- Probe name: A_24_P303589
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.26 ± 0.4 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.13 ± 0.19 | |
| Basal Part of Pons | 7.41 ± 0.22 | |
| Cerebellar Cortex | 7.22 ± 0.27 | |
| Cerebellar Nuclei | 7.09 ± 0.23 | |
| Claustrum | 7.39 ± 0.31 | |
| Epithalamus | 7.01 ± 0.21 | |
| Frontal Lobe | 7.29 ± 0.29 | |
| Globus Pallidus | 6.83 ± 0.18 | |
| Hypothalamus | 7.08 ± 0.17 | |
| Insula | 7.27 ± 0.34 | |
| Limbic Lobe | 7.38 ± 0.25 | |
| Mesencephalon | 7.08 ± 0.29 | |
| Myelencephalon | 7.22 ± 0.3 | |
| Occipital Lobe | 7.19 ± 0.33 | |
| Parietal Lobe | 7.31 ± 0.25 | |
| Pontine Tegmentum | 7.2 ± 0.28 | |
| Striatum | 7.05 ± 0.22 | |
| Subthalamus | 7.28 ± 0.05 | |
| Temporal Lobe | 7.33 ± 0.26 | |
| Thalamus | 7.2 ± 0.29 | |
| White Matter | 6.67 ± 0.32 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cul1 | CB | Cerebellum | 47 | |
| 67.33 | | |||
| Cul1 | CTX | Cerebral cortex | 100 | |
| 99.47 | | |||
| Cul1 | HIP | Hippocampal region | 73.18 | |
| 100 | | |||
| Cul1 | HPF | Hippocampal formation | 94.41 | |
| 100 | | |||
| Cul1 | HY | Hypothalamus | 88.23 | |
| 81.24 | | |||
| Cul1 | LSX | Lateral septal complex | 100 | |
| 97.76 | | |||
| Cul1 | MB | Midbrain | 71.16 | |
| 75.91 | | |||
| Cul1 | MY | Medulla | 33.67 | |
| 51.79 | | |||
| Cul1 | OLF | Olfactory bulb | 71.21 | |
| 82.25 | | |||
| Cul1 | P | Pons | 51.97 | |
| 69.35 | | |||
| Cul1 | PAL | Pallidum | 83.53 | |
| 89.53 | | |||
| Cul1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Cul1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Cul1 | STR | Striatum | 75.77 | |
| 66.15 | | |||
| Cul1 | STRd | Striatum dorsal region | 59.41 | |
| 51.36 | | |||
| Cul1 | STRv | Striatum ventral region | 82.82 | |
| 70.64 | | |||
| Cul1 | TH | Thalamus | 89.93 | |
| 89.13 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00029973 | 16 | 75 | 90 | GQTPGGAQFVGLELYK | Peptide Atlas |