AutismKB 2.0

Annotation Detail for TTF2


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Basic Information Top
Gene Symbol:TTF2 ( HuF2 )
Gene Full Name: transcription termination factor, RNA polymerase II
Band: 1p13.1
Quick LinksEntrez ID:8458; OMIM: 604718; Uniprot ID:TTF2_HUMAN; ENSEMBL ID: ENSG00000116830; HGNC ID: 12398
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus13 / 56401223
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor39 / 94178414
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal67 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor10 / 12494980
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain18 / 110098916
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye3 / 21105414
heart2 / 8962622
intestine5 / 23447221
kidney7 / 21177733
larynx1 / 2414541
liver8 / 20774338
lung0 / 3369740 
lymph0 / 442700 
lymph node4 / 9161043
mammary gland40 / 153271260
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate4 / 18934521
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach3 / 9661931
testis9 / 33044227
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204407_at
Cell line Expression level Expression bar
721_B_lymphoblasts49.65
Adipocyte8.15
AdrenalCortex12.25
Adrenalgland8.1
Amygdala7.9
Appendix11.4
AtrioventricularNode10.95
BDCA4+_DentriticCells7.7
Bonemarrow11.8
BronchialEpithelialCells8.2
CD105+_Endothelial8.95
CD14+_Monocytes9.25
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid11.2
CD34+11.1
CD4+_Tcells8.3
CD56+_NKCells9.6
CD71+_EarlyErythroid10.1
CD8+_Tcells8.5
CardiacMyocytes19.3
Caudatenucleus7.65
Cerebellum6.9
CerebellumPeduncles11.05
CiliaryGanglion11.65
CingulateCortex9.1
Colorectaladenocarcinoma46.5
DorsalRootGanglion9.1
FetalThyroid8.8
Fetalbrain7.5
Fetalliver8.05
Fetallung5.75
GlobusPallidus7.1
Heart15.8
Hypothalamus8.15
Kidney8.1
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-6032.75
Leukemialymphoblastic(MOLT-4)9.4
Liver15.05
Lung9.2
Lymphnode7.15
Lymphoma_burkitts(Daudi)28.95
Lymphoma_burkitts(Raji)44.1
MedullaOblongata6.8
OccipitalLobe7.4
OlfactoryBulb6.4
Ovary6.65
Pancreas7.6
PancreaticIslet9.15
ParietalLobe10
Pituitary9.4
Placenta7.65
Pons8.75
PrefrontalCortex9.25
Prostate9.6
Salivarygland8.05
SkeletalMuscle17.55
Skin9.7
SmoothMuscle9.5
Spinalcord8.95
SubthalamicNucleus9.4
SuperiorCervicalGanglion22.25
TemporalLobe8.5
Testis7.3
TestisGermCell6.25
TestisIntersitial7.65
TestisLeydigCell9
TestisSeminiferousTubule7.35
Thalamus8.8
Thymus6.9
Thyroid13.3
Tongue12.1
Tonsil9.85
Trachea6.7
TrigeminalGanglion40.15
Uterus6.75
UterusCorpus10.05
WholeBlood8.85
Wholebrain6.2
colon35.65
pineal_day12.2
pineal_night12.08
retina10.425
small_intestine8.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4748_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.36 ± 0.58
Basal Forebrain5.85 ± 0.28
Basal Part of Pons5.25 ± 0.33
Cerebellar Cortex5.12 ± 0.31
Cerebellar Nuclei6.11 ± 0.48
Claustrum5.08 ± 0.85
Epithalamus6.07 ± 0.36
Frontal Lobe5.6 ± 0.45
Globus Pallidus6.68 ± 0.28
Hypothalamus5.84 ± 0.35
Insula5.51 ± 0.47
Limbic Lobe5.45 ± 0.58
Mesencephalon5.85 ± 0.44
Myelencephalon5.69 ± 0.48
Occipital Lobe5.65 ± 0.42
Parietal Lobe5.58 ± 0.53
Pontine Tegmentum5.79 ± 0.39
Striatum6.13 ± 0.34
Subthalamus6.28 ± 0.39
Temporal Lobe5.59 ± 0.42
Thalamus5.95 ± 0.32
White Matter7.44 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ttf2CBCerebellum1.99
3.54
Ttf2CTXCerebral cortex1.53
1.7
Ttf2HIPHippocampal region0.31
0.45
Ttf2HPFHippocampal formation0.25
0.44
Ttf2HYHypothalamus1.16
0.93
Ttf2LSXLateral septal complex0.1
0.09
Ttf2MBMidbrain2.57
2.78
Ttf2MYMedulla3.21
3.67
Ttf2OLFOlfactory bulb0.85
1.65
Ttf2PPons4.75
5.23
Ttf2PALPallidum0.27
0.21
Ttf2RHPRetrohippocampal region0.15
0.47
Ttf2sAMYStriatum-like amygdalar nuclei0.28
0.25
Ttf2STRStriatum0.34
0.31
Ttf2STRdStriatum dorsal region0.36
0.34
Ttf2STRvStriatum ventral region0.41
0.31
Ttf2THThalamus3.61
4.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042640 19 221 239 SQQCQGNELTRPSASSQEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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