AutismKB 2.0

Annotation Detail for ZNF469


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Basic Information Top
Gene Symbol:ZNF469 ( BCS,KIAA1858 )
Gene Full Name: zinc finger protein 469
Band: 16q24.2
Quick LinksEntrez ID:84627; OMIM: 612078; Uniprot ID:ZN469_HUMAN; ENSEMBL ID: ENSG00000225614; HGNC ID: 23216
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal10 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P116556
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.51 ± 0.49
Basal Forebrain6.8 ± 0.4
Basal Part of Pons6.44 ± 0.4
Cerebellar Cortex6.28 ± 0.46
Cerebellar Nuclei7.05 ± 0.4
Claustrum6.08 ± 0.66
Epithalamus6.39 ± 0.56
Frontal Lobe7.17 ± 0.63
Globus Pallidus7.16 ± 0.5
Hypothalamus6.54 ± 0.35
Insula7.4 ± 0.51
Limbic Lobe7.41 ± 0.8
Mesencephalon7.15 ± 0.55
Myelencephalon7.08 ± 0.57
Occipital Lobe6.68 ± 0.62
Parietal Lobe7.24 ± 0.58
Pontine Tegmentum7.16 ± 0.6
Striatum8.17 ± 0.35
Subthalamus6.39 ± 0.34
Temporal Lobe7.05 ± 0.58
Thalamus6.93 ± 0.43
White Matter5.72 ± 0.81
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gm22CBCerebellum8.27
7.73
Gm22CTXCerebral cortex18.35
9.78
Gm22HIPHippocampal region11.07
9.83
Gm22HPFHippocampal formation11.61
7.67
Gm22HYHypothalamus4.89
2.04
Gm22LSXLateral septal complex8.36
2.73
Gm22MBMidbrain2.45
1.9
Gm22MYMedulla8.52
5.83
Gm22OLFOlfactory bulb26.33
19.11
Gm22PPons10.37
8.06
Gm22PALPallidum7.63
3.96
Gm22RHPRetrohippocampal region11.88
5.21
Gm22sAMYStriatum-like amygdalar nuclei8.29
2.8
Gm22STRStriatum6.75
3.15
Gm22STRdStriatum dorsal region6.15
2.85
Gm22STRvStriatum ventral region7.91
4.49
Gm22THThalamus13.32
6.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ZN469_HUMAN_19 10 19 28 ASPAGGQARR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018