Annotation Detail for AFAP1L2
Basic Information Top
| Gene Symbol: | AFAP1L2 ( FLJ14564,KIAA1914,XB130 ) |
|---|---|
| Gene Full Name: | actin filament associated protein 1-like 2 |
| Band: | 10q25.3 |
| Quick Links | Entrez ID:84632; OMIM: 612420; Uniprot ID:AF1L2_HUMAN; ENSEMBL ID: ENSG00000169129; HGNC ID: 25901 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.501106
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 13 / 564012 | 23 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 60 / 1939121 | 30 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 1 / 17290 | 57 |  |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 102 / 3360307 | 30 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 7 / 125680 | 55 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 3 / 123478 | 24 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 38 / 1100989 | 34 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 6 / 211054 | 28 | |
| heart | 1 / 89626 | 11 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 15 / 280825 | 53 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 5 / 53952 | 92 | |
| stomach | 1 / 96619 | 10 | |
| testis | 5 / 330442 | 15 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 9 / 47473 | 189 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 10 / 232878 | 42 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_24_P33770
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.15 ± 0.6 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.18 ± 0.36 | |
| Basal Part of Pons | 4.07 ± 0.68 | |
| Cerebellar Cortex | 4.57 ± 0.34 | |
| Cerebellar Nuclei | 4.49 ± 0.39 | |
| Claustrum | 4.32 ± 0.84 | |
| Epithalamus | 3.7 ± 0.59 | |
| Frontal Lobe | 4.2 ± 0.57 | |
| Globus Pallidus | 4.61 ± 0.55 | |
| Hypothalamus | 3.94 ± 0.55 | |
| Insula | 4.21 ± 0.42 | |
| Limbic Lobe | 4.01 ± 0.58 | |
| Mesencephalon | 4.23 ± 0.57 | |
| Myelencephalon | 4.1 ± 0.57 | |
| Occipital Lobe | 3.93 ± 0.42 | |
| Parietal Lobe | 4.06 ± 0.52 | |
| Pontine Tegmentum | 4.14 ± 0.62 | |
| Striatum | 3.71 ± 0.64 | |
| Subthalamus | 4.5 ± 0.77 | |
| Temporal Lobe | 4.11 ± 0.53 | |
| Thalamus | 4.19 ± 0.53 | |
| White Matter | 3.78 ± 0.6 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| AU041783 | CB | Cerebellum | 100 | |
| 100 | | |||
| AU041783 | CTX | Cerebral cortex | 4.91 | |
| 3.82 | | |||
| AU041783 | HIP | Hippocampal region | 2.27 | |
| 2.41 | | |||
| AU041783 | HPF | Hippocampal formation | 1.36 | |
| 1.34 | | |||
| AU041783 | HY | Hypothalamus | 0.47 | |
| 0.39 | | |||
| AU041783 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| AU041783 | MB | Midbrain | 0.44 | |
| 0.61 | | |||
| AU041783 | MY | Medulla | 3.53 | |
| 3.66 | | |||
| AU041783 | OLF | Olfactory bulb | 11.33 | |
| 10.81 | | |||
| AU041783 | P | Pons | 0.28 | |
| 0.26 | | |||
| AU041783 | PAL | Pallidum | 1.9 | |
| 2.3 | | |||
| AU041783 | RHP | Retrohippocampal region | 0.45 | |
| 0.37 | | |||
| AU041783 | sAMY | Striatum-like amygdalar nuclei | 3.44 | |
| 2.6 | | |||
| AU041783 | STR | Striatum | 1.45 | |
| 1.25 | | |||
| AU041783 | STRd | Striatum dorsal region | 1.16 | |
| 1.12 | | |||
| AU041783 | STRv | Striatum ventral region | 0.87 | |
| 0.42 | | |||
| AU041783 | TH | Thalamus | 2.64 | |
| 2.46 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| AF1L2_HUMAN_416 | 14 | 416 | 429 | ILHKGEELAKLEAK | PRIDE |
| AF1L2_HUMAN_5 | 14 | 5 | 18 | ALEQLLTELDDFLK | PRIDE |
| PAp00095447 | 20 | 772 | 791 | AVTPASAPDCTPVNSATTLK | Peptide Atlas |