AutismKB 2.0

Annotation Detail for GLIS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GLIS2 ( FLJ38247,NKL,NPHP7 )
Gene Full Name: GLIS family zinc finger 2
Band: 16p13.3
Quick LinksEntrez ID:84662; OMIM: 608539; Uniprot ID:GLIS2_HUMAN; ENSEMBL ID: ENSG00000126603; HGNC ID: 29450
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma10 / 10688393
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal73 / 336030721
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain22 / 110098919
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye8 / 21105437
heart0 / 896260 
intestine6 / 23447225
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate0 / 1893450 
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1679_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 0.95
Basal Forebrain3.66 ± 0.61
Basal Part of Pons3.77 ± 0.38
Cerebellar Cortex4.09 ± 0.58
Cerebellar Nuclei4.18 ± 0.75
Claustrum4.48 ± 0.81
Epithalamus3.3 ± 0.66
Frontal Lobe3.7 ± 0.73
Globus Pallidus3.91 ± 1.24
Hypothalamus3.48 ± 0.68
Insula3.36 ± 0.69
Limbic Lobe3.8 ± 0.67
Mesencephalon3.83 ± 0.81
Myelencephalon3.86 ± 0.73
Occipital Lobe4.14 ± 0.78
Parietal Lobe3.9 ± 0.6
Pontine Tegmentum3.92 ± 0.72
Striatum3.69 ± 0.62
Subthalamus3.56 ± 0.27
Temporal Lobe3.63 ± 0.71
Thalamus3.91 ± 0.54
White Matter3.45 ± 0.84
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Glis2CBCerebellum9.4
8.3
Glis2CTXCerebral cortex49.4
18.74
Glis2HIPHippocampal region18.45
11.2
Glis2HPFHippocampal formation26.11
13.6
Glis2HYHypothalamus36
15.98
Glis2LSXLateral septal complex4.92
1.49
Glis2MBMidbrain39.34
19.21
Glis2MYMedulla51.59
33.36
Glis2OLFOlfactory bulb54.77
28.71
Glis2PPons41.96
27.17
Glis2PALPallidum27.92
12.69
Glis2RHPRetrohippocampal region45.51
19.39
Glis2sAMYStriatum-like amygdalar nuclei23.19
9.23
Glis2STRStriatum14.55
6.5
Glis2STRdStriatum dorsal region13.27
6.09
Glis2STRvStriatum ventral region16.37
7.38
Glis2THThalamus16.06
6.92
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018