AutismKB 2.0

Annotation Detail for CARD6


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Basic Information Top
Gene Symbol:CARD6 ( CINCIN1 )
Gene Full Name: caspase recruitment domain family, member 6
Band: 5p13.1
Quick LinksEntrez ID:84674; OMIM: 609986; Uniprot ID:CARD6_HUMAN; ENSEMBL ID: ENSG00000132357; HGNC ID: 16394
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland1 / 2015549
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1607_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.73 ± 0.6
Basal Forebrain5 ± 0.28
Basal Part of Pons4.69 ± 0.37
Cerebellar Cortex4.87 ± 0.3
Cerebellar Nuclei5.87 ± 0.52
Claustrum4.93 ± 0.59
Epithalamus5.65 ± 0.5
Frontal Lobe4.87 ± 0.6
Globus Pallidus6.61 ± 0.39
Hypothalamus5.36 ± 0.39
Insula4.92 ± 0.53
Limbic Lobe4.9 ± 0.69
Mesencephalon5.36 ± 0.49
Myelencephalon5.13 ± 0.55
Occipital Lobe5.11 ± 0.66
Parietal Lobe4.92 ± 0.62
Pontine Tegmentum5.08 ± 0.72
Striatum5.63 ± 0.65
Subthalamus4.92 ± 0.32
Temporal Lobe4.88 ± 0.59
Thalamus5.22 ± 0.43
White Matter6 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Card6CBCerebellum100
100
Card6CTXCerebral cortex89.22
73.07
Card6HIPHippocampal region61.56
92.23
Card6HPFHippocampal formation55.99
69.54
Card6HYHypothalamus40.84
33.36
Card6LSXLateral septal complex51.71
42.38
Card6MBMidbrain50.58
47.49
Card6MYMedulla39.52
47.72
Card6OLFOlfactory bulb88.04
100
Card6PPons36.9
36.48
Card6PALPallidum49.03
44.42
Card6RHPRetrohippocampal region47.34
40.71
Card6sAMYStriatum-like amygdalar nuclei60.41
51.82
Card6STRStriatum66.36
57.3
Card6STRdStriatum dorsal region63.53
53.57
Card6STRvStriatum ventral region79.95
71.4
Card6THThalamus45.49
38.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CARD6_HUMAN_2 12 2 13 ATESTPSEIIER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018