AutismKB 2.0

Annotation Detail for ACCS


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Basic Information Top
Gene Symbol:ACCS ( ACS,PHACS )
Gene Full Name: 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
Band: 11p11.2
Quick LinksEntrez ID:84680; OMIM: 608405; Uniprot ID:1A1L1_HUMAN; ENSEMBL ID: ENSG00000110455; HGNC ID: 23989
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal103 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder2 / 2975767
blood3 / 12347824
bone2 / 7165527
bone marrow3 / 4880161
brain21 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine8 / 23447234
kidney4 / 21177718
larynx1 / 2414541
liver10 / 20774348
lung5 / 33697414
lymph0 / 442700 
lymph node5 / 9161054
mammary gland2 / 15327113
mouth1 / 6705214
muscle9 / 10771583
nerve2 / 15768126
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate7 / 18934536
salivary gland0 / 201550 
skin4 / 21057418
spleen3 / 5395255
stomach6 / 9661962
testis13 / 33044239
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus23 / 23287898
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P24586
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 0.56
Basal Forebrain4.06 ± 0.77
Basal Part of Pons3.66 ± 0.47
Cerebellar Cortex4.5 ± 0.43
Cerebellar Nuclei4.05 ± 0.56
Claustrum3.39 ± 0.74
Epithalamus4.99 ± 0.73
Frontal Lobe4.02 ± 0.53
Globus Pallidus4.23 ± 0.57
Hypothalamus4.03 ± 0.61
Insula4.14 ± 0.55
Limbic Lobe4.01 ± 0.58
Mesencephalon4.16 ± 0.5
Myelencephalon4.1 ± 0.6
Occipital Lobe4.03 ± 0.63
Parietal Lobe3.96 ± 0.57
Pontine Tegmentum3.98 ± 0.61
Striatum3.97 ± 0.53
Subthalamus4.15 ± 0.76
Temporal Lobe4.09 ± 0.55
Thalamus3.9 ± 0.59
White Matter3.85 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2610203E10RikCBCerebellum0.17
0.51
2610203E10RikCTXCerebral cortex3.42
2.62
2610203E10RikHIPHippocampal region0.32
0.4
2610203E10RikHPFHippocampal formation0.25
0.31
2610203E10RikHYHypothalamus3.26
4.99
2610203E10RikLSXLateral septal complex0.1
0.1
2610203E10RikMBMidbrain0.17
0.43
2610203E10RikMYMedulla0.66
1.09
2610203E10RikOLFOlfactory bulb2.95
2.51
2610203E10RikPPons1.65
3.41
2610203E10RikPALPallidum0.97
0.82
2610203E10RikRHPRetrohippocampal region0.11
0.18
2610203E10RiksAMYStriatum-like amygdalar nuclei0.84
0.75
2610203E10RikSTRStriatum0.92
0.68
2610203E10RikSTRdStriatum dorsal region0.98
0.72
2610203E10RikSTRvStriatum ventral region1.36
0.9
2610203E10RikTHThalamus0.21
0.2
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018