AutismKB 2.0

Annotation Detail for PPP1R9B


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Basic Information Top
Gene Symbol:PPP1R9B ( FLJ30345,PPP1R6,PPP1R9,SPINO,Spn )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 9B
Band: 17q21.33
Quick LinksEntrez ID:84687; OMIM: 603325; Uniprot ID:NEB2_HUMAN; ENSEMBL ID: ENSG00000108819; HGNC ID: 9298
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor5 / 26384518
glioma11 / 106883102
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia15 / 95842156
liver tumor0 / 963590 
lung tumor8 / 10312777
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal83 / 336030724
ovarian tumor5 / 7668265
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain33 / 110098929
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine8 / 23447234
kidney7 / 21177733
larynx1 / 2414541
liver1 / 2077434
lung15 / 33697444
lymph5 / 44270112
lymph node5 / 9161054
mammary gland5 / 15327132
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate2 / 18934510
salivary gland3 / 20155148
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P376309
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.4 ± 0.47
Basal Forebrain11.03 ± 0.09
Basal Part of Pons11.25 ± 0.21
Cerebellar Cortex11.07 ± 0.24
Cerebellar Nuclei10.35 ± 0.5
Claustrum11.3 ± 0.3
Epithalamus10.43 ± 0.29
Frontal Lobe11.12 ± 0.39
Globus Pallidus9.98 ± 0.38
Hypothalamus10.42 ± 0.3
Insula11.3 ± 0.21
Limbic Lobe11.47 ± 0.36
Mesencephalon10.86 ± 0.34
Myelencephalon11.09 ± 0.33
Occipital Lobe11.03 ± 0.3
Parietal Lobe11.19 ± 0.41
Pontine Tegmentum10.96 ± 0.31
Striatum11.44 ± 0.31
Subthalamus10.53 ± 0.18
Temporal Lobe11.28 ± 0.31
Thalamus11.17 ± 0.34
White Matter9.56 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ppp1r9bCBCerebellum100
100
Ppp1r9bCTXCerebral cortex100
100
Ppp1r9bHIPHippocampal region100
100
Ppp1r9bHPFHippocampal formation100
100
Ppp1r9bHYHypothalamus100
100
Ppp1r9bLSXLateral septal complex100
100
Ppp1r9bMBMidbrain100
100
Ppp1r9bMYMedulla100
100
Ppp1r9bOLFOlfactory bulb100
100
Ppp1r9bPPons100
100
Ppp1r9bPALPallidum100
100
Ppp1r9bRHPRetrohippocampal region100
100
Ppp1r9bsAMYStriatum-like amygdalar nuclei100
100
Ppp1r9bSTRStriatum100
100
Ppp1r9bSTRdStriatum dorsal region100
100
Ppp1r9bSTRvStriatum ventral region100
100
Ppp1r9bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018