AutismKB 2.0

Annotation Detail for GJA10


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Basic Information Top
Gene Symbol:GJA10 ( CX62,RP11-63K6.6 )
Gene Full Name: gap junction protein, alpha 10, 62kDa
Band: 6q15
Quick LinksEntrez ID:84694; OMIM: 611924; Uniprot ID:CXA10_HUMAN; ENSEMBL ID: ENSG00000135355; HGNC ID: 16995
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11624_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.57 ± 0.87
Basal Forebrain3.04 ± 0.42
Basal Part of Pons3.19 ± 1
Cerebellar Cortex3.29 ± 0.78
Cerebellar Nuclei3.41 ± 0.76
Claustrum3.9 ± 0.91
Epithalamus2.73 ± 0.64
Frontal Lobe3.07 ± 0.85
Globus Pallidus3.18 ± 0.97
Hypothalamus2.98 ± 0.59
Insula3.3 ± 1.26
Limbic Lobe3.27 ± 0.81
Mesencephalon3.08 ± 0.8
Myelencephalon3.25 ± 0.74
Occipital Lobe3.21 ± 0.9
Parietal Lobe3.18 ± 0.8
Pontine Tegmentum3.15 ± 0.75
Striatum2.99 ± 0.8
Subthalamus3.14 ± 0.08
Temporal Lobe3.22 ± 0.76
Thalamus3.16 ± 0.75
White Matter3 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gja10CBCerebellum29.6
33
Gja10CTXCerebral cortex55.06
44.66
Gja10HIPHippocampal region33.37
40.16
Gja10HPFHippocampal formation33.68
33.92
Gja10HYHypothalamus74.51
77.56
Gja10LSXLateral septal complex38.85
30.04
Gja10MBMidbrain39.09
37.17
Gja10MYMedulla34.93
38.62
Gja10OLFOlfactory bulb58.5
55.77
Gja10PPons31.48
33.19
Gja10PALPallidum50.82
51.73
Gja10RHPRetrohippocampal region34.15
26.32
Gja10sAMYStriatum-like amygdalar nuclei27.29
19.02
Gja10STRStriatum36.45
31.18
Gja10STRdStriatum dorsal region27.83
23.34
Gja10STRvStriatum ventral region75.71
66.5
Gja10THThalamus44.65
43.72
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018