Annotation Detail for LNX1
Basic Information Top
| Gene Symbol: | LNX1 ( LNX,MPDZ,PDZRN2 ) |
|---|---|
| Gene Full Name: | ligand of numb-protein X 1 |
| Band: | 4q12 |
| Quick Links | Entrez ID:84708; OMIM: 609732; Uniprot ID:LNX1_HUMAN; ENSEMBL ID: ENSG00000072201; HGNC ID: 6657 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.518760
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 38 / 564012 | 67 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 52 / 1939121 | 26 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 131 / 3360307 | 38 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 17 / 125191 | 135 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 90 / 1100989 | 81 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 18 / 149255 | 120 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 1 / 89626 | 11 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 5 / 336974 | 14 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 12 / 67052 | 178 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 10 / 330442 | 30 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P213137
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.01 ± 0.53 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.86 ± 0.32 | |
| Basal Part of Pons | 7.53 ± 0.47 | |
| Cerebellar Cortex | 7.28 ± 0.18 | |
| Cerebellar Nuclei | 7.53 ± 0.52 | |
| Claustrum | 8.94 ± 0.4 | |
| Epithalamus | 6.92 ± 0.92 | |
| Frontal Lobe | 7.95 ± 0.53 | |
| Globus Pallidus | 6.38 ± 1.23 | |
| Hypothalamus | 7.88 ± 0.33 | |
| Insula | 8.1 ± 0.25 | |
| Limbic Lobe | 7.85 ± 0.65 | |
| Mesencephalon | 7.77 ± 0.66 | |
| Myelencephalon | 7.78 ± 0.64 | |
| Occipital Lobe | 8.33 ± 0.64 | |
| Parietal Lobe | 8.04 ± 0.55 | |
| Pontine Tegmentum | 8.01 ± 0.73 | |
| Striatum | 8.16 ± 0.75 | |
| Subthalamus | 7.54 ± 0.12 | |
| Temporal Lobe | 8.14 ± 0.44 | |
| Thalamus | 7.91 ± 0.64 | |
| White Matter | 5.69 ± 0.84 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Lnx1 | CB | Cerebellum | 0.42 | |
| 1.1 | | |||
| Lnx1 | CTX | Cerebral cortex | 5.22 | |
| 3.78 | | |||
| Lnx1 | HIP | Hippocampal region | 8.45 | |
| 7.92 | | |||
| Lnx1 | HPF | Hippocampal formation | 5.84 | |
| 5.19 | | |||
| Lnx1 | HY | Hypothalamus | 0.16 | |
| 0.18 | | |||
| Lnx1 | LSX | Lateral septal complex | 0.08 | |
| 0.05 | | |||
| Lnx1 | MB | Midbrain | 0.87 | |
| 0.89 | | |||
| Lnx1 | MY | Medulla | 2.29 | |
| 2.27 | | |||
| Lnx1 | OLF | Olfactory bulb | 4.9 | |
| 4.22 | | |||
| Lnx1 | P | Pons | 1.49 | |
| 1.9 | | |||
| Lnx1 | PAL | Pallidum | 0.76 | |
| 1.25 | | |||
| Lnx1 | RHP | Retrohippocampal region | 1.5 | |
| 1.42 | | |||
| Lnx1 | sAMY | Striatum-like amygdalar nuclei | 1.59 | |
| 0.99 | | |||
| Lnx1 | STR | Striatum | 0.81 | |
| 0.74 | | |||
| Lnx1 | STRd | Striatum dorsal region | 0.73 | |
| 0.75 | | |||
| Lnx1 | STRv | Striatum ventral region | 1.13 | |
| 0.88 | | |||
| Lnx1 | TH | Thalamus | 1.08 | |
| 0.97 | |