AutismKB 2.0

Annotation Detail for HIRIP3


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Basic Information Top
Gene Symbol:HIRIP3 ( - )
Gene Full Name: HIRA interacting protein 3
Band: 16p11.2
Quick LinksEntrez ID:8479; OMIM: 603365; Uniprot ID:HIRP3_HUMAN; ENSEMBL ID: ENSG00000149929; HGNC ID: 4917
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus15 / 56401226
neonate3 / 3109796
infant0 / 236200 
juvenile5 / 5555689
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor6 / 26384522
glioma6 / 10688356
head and neck tumor7 / 13630251
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor13 / 96359134
lung tumor16 / 103127155
lymphoma8 / 71755111
non-neoplasia4 / 9725041
normal139 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS32 / 125680254
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor13 / 124949104
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood5 / 12347840
bone5 / 7165569
bone marrow3 / 4880161
brain68 / 110098961
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye8 / 21105437
heart8 / 8962689
intestine11 / 23447246
kidney7 / 21177733
larynx1 / 2414541
liver17 / 20774381
lung28 / 33697483
lymph2 / 4427045
lymph node0 / 916100 
mammary gland7 / 15327145
mouth3 / 6705244
muscle6 / 10771555
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate9 / 18934547
salivary gland2 / 2015599
skin16 / 21057475
spleen4 / 5395274
stomach2 / 9661920
testis15 / 33044245
thymus7 / 8113186
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204504_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts58.75
Adipocyte10.6
AdrenalCortex11.65
Adrenalgland11.95
Amygdala10.65
Appendix13.05
AtrioventricularNode10
BDCA4+_DentriticCells15.8
Bonemarrow18.5
BronchialEpithelialCells11.85
CD105+_Endothelial17.2
CD14+_Monocytes7.2
CD19+_BCells(neg._sel.)12
CD33+_Myeloid12.55
CD34+18.3
CD4+_Tcells13.45
CD56+_NKCells12.85
CD71+_EarlyErythroid24.8
CD8+_Tcells11.75
CardiacMyocytes20.45
Caudatenucleus12.45
Cerebellum13.05
CerebellumPeduncles15.55
CiliaryGanglion6.05
CingulateCortex13.7
Colorectaladenocarcinoma19
DorsalRootGanglion9.95
FetalThyroid13.2
Fetalbrain13.5
Fetalliver13.45
Fetallung11.25
GlobusPallidus9.75
Heart24.9
Hypothalamus14.7
Kidney10.15
Leukemia_chronicMyelogenousK-56212.15
Leukemia_promyelocytic-HL-6011.9
Leukemialymphoblastic(MOLT-4)23.6
Liver23.25
Lung20.7
Lymphnode11.75
Lymphoma_burkitts(Daudi)28.85
Lymphoma_burkitts(Raji)18.65
MedullaOblongata12.1
OccipitalLobe11.95
OlfactoryBulb9.5
Ovary8.35
Pancreas10.8
PancreaticIslet13.95
ParietalLobe12.6
Pituitary17.25
Placenta13.9
Pons10.5
PrefrontalCortex17.1
Prostate15.75
Salivarygland9.8
SkeletalMuscle15.05
Skin9.65
SmoothMuscle15.3
Spinalcord17.85
SubthalamicNucleus13.95
SuperiorCervicalGanglion15.7
TemporalLobe11
Testis17.75
TestisGermCell16.45
TestisIntersitial17.25
TestisLeydigCell25
TestisSeminiferousTubule19.1
Thalamus13.7
Thymus18.8
Thyroid20.85
Tongue12.85
Tonsil13.1
Trachea11.2
TrigeminalGanglion10.1
Uterus17.6
UterusCorpus12.7
WholeBlood15.4
Wholebrain17.65
colon11.6
pineal_day15.36
pineal_night16.34
retina16.025
small_intestine8.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13062_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.68 ± 0.97
Basal Forebrain3.32 ± 0.38
Basal Part of Pons3.37 ± 0.68
Cerebellar Cortex3.54 ± 0.68
Cerebellar Nuclei3.45 ± 0.44
Claustrum4.03 ± 0.61
Epithalamus3.17 ± 0.65
Frontal Lobe3.33 ± 0.62
Globus Pallidus3.73 ± 0.63
Hypothalamus3.29 ± 0.49
Insula3.29 ± 0.77
Limbic Lobe3.49 ± 0.69
Mesencephalon3.5 ± 0.68
Myelencephalon3.46 ± 0.68
Occipital Lobe3.77 ± 0.63
Parietal Lobe3.54 ± 0.6
Pontine Tegmentum3.59 ± 0.74
Striatum3.53 ± 0.85
Subthalamus3.48 ± 0.27
Temporal Lobe3.39 ± 0.62
Thalamus3.39 ± 0.62
White Matter3.79 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hirip3CBCerebellum46.37
58.51
Hirip3CTXCerebral cortex100
100
Hirip3HIPHippocampal region67.11
100
Hirip3HPFHippocampal formation82
100
Hirip3HYHypothalamus100
92.18
Hirip3LSXLateral septal complex95.31
72.98
Hirip3MBMidbrain85.55
81.46
Hirip3MYMedulla82.36
96.71
Hirip3OLFOlfactory bulb100
100
Hirip3PPons81.66
91.28
Hirip3PALPallidum98.41
100
Hirip3RHPRetrohippocampal region100
99.78
Hirip3sAMYStriatum-like amygdalar nuclei100
100
Hirip3STRStriatum100
100
Hirip3STRdStriatum dorsal region100
100
Hirip3STRvStriatum ventral region100
100
Hirip3THThalamus93.1
83.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HIRP3_HUMAN_40 13 40 52 SHLEPEEKQALKR PRIDE
PAp00068848 14 17 30 GRPDLSTLTHSIVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018