AutismKB 2.0

Annotation Detail for PYROXD2


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Basic Information Top
Gene Symbol:PYROXD2 ( C10orf33,FLJ12197,FLJ23849,FP3420,MGC13047 )
Gene Full Name: pyridine nucleotide-disulphide oxidoreductase domain 2
Band: 10q24.2
Quick LinksEntrez ID:84795; OMIM: NA; Uniprot ID:PYRD2_HUMAN; ENSEMBL ID: ENSG00000119943; HGNC ID: 23517
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal71 / 336030721
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain23 / 110098920
cervix7 / 48171145
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart3 / 8962633
intestine4 / 23447217
kidney6 / 21177728
larynx1 / 2414541
liver1 / 2077434
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach4 / 9661941
testis1 / 3304423
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P24157
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.57
Basal Forebrain4.66 ± 0.54
Basal Part of Pons4.13 ± 0.47
Cerebellar Cortex4.21 ± 0.36
Cerebellar Nuclei4.15 ± 0.62
Claustrum3.82 ± 0.83
Epithalamus5.51 ± 0.62
Frontal Lobe4.24 ± 0.62
Globus Pallidus5.48 ± 0.28
Hypothalamus4.24 ± 0.58
Insula4.11 ± 0.52
Limbic Lobe4.17 ± 0.62
Mesencephalon4.48 ± 0.51
Myelencephalon4.46 ± 0.6
Occipital Lobe4.53 ± 0.38
Parietal Lobe4.3 ± 0.58
Pontine Tegmentum4.22 ± 0.61
Striatum5.08 ± 0.43
Subthalamus3.68 ± 0.28
Temporal Lobe4.2 ± 0.48
Thalamus4.55 ± 0.44
White Matter6.12 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4833409A17RikCBCerebellum1.73
2.75
4833409A17RikCTXCerebral cortex1.24
1.84
4833409A17RikHIPHippocampal region0.96
1.18
4833409A17RikHPFHippocampal formation0.78
0.94
4833409A17RikHYHypothalamus0.52
0.6
4833409A17RikLSXLateral septal complex0.19
0.15
4833409A17RikMBMidbrain0.65
0.98
4833409A17RikMYMedulla1.42
1.56
4833409A17RikOLFOlfactory bulb0.62
0.71
4833409A17RikPPons0.48
0.57
4833409A17RikPALPallidum1.07
1.15
4833409A17RikRHPRetrohippocampal region0.42
0.49
4833409A17RiksAMYStriatum-like amygdalar nuclei0.53
0.57
4833409A17RikSTRStriatum0.49
0.58
4833409A17RikSTRdStriatum dorsal region0.51
0.6
4833409A17RikSTRvStriatum ventral region0.43
0.37
4833409A17RikTHThalamus1.11
1.83
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018