AutismKB 2.0

Annotation Detail for RTN4IP1


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Basic Information Top
Gene Symbol:RTN4IP1 ( MGC12934,NIMP )
Gene Full Name: reticulon 4 interacting protein 1
Band: 6q21
Quick LinksEntrez ID:84816; OMIM: 610502; Uniprot ID:RT4I1_HUMAN; ENSEMBL ID: ENSG00000130347; HGNC ID: 18647
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal41 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer9 / 10268087
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain10 / 11009899
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver4 / 20774319
lung8 / 33697423
lymph1 / 4427022
lymph node3 / 9161032
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta3 / 28082510
prostate9 / 18934547
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach4 / 9661941
testis10 / 33044230
thymus1 / 8113112
thyroid1 / 4747321
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1122_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.59 ± 0.58
Basal Forebrain4.17 ± 0.48
Basal Part of Pons4.38 ± 0.33
Cerebellar Cortex4.95 ± 0.22
Cerebellar Nuclei4.3 ± 0.45
Claustrum4.23 ± 0.69
Epithalamus4.98 ± 0.42
Frontal Lobe4.61 ± 0.42
Globus Pallidus4.2 ± 0.49
Hypothalamus4.42 ± 0.39
Insula4.6 ± 0.41
Limbic Lobe4.48 ± 0.54
Mesencephalon4.66 ± 0.63
Myelencephalon4.47 ± 0.5
Occipital Lobe4.37 ± 0.39
Parietal Lobe4.58 ± 0.5
Pontine Tegmentum4.62 ± 0.51
Striatum4.17 ± 0.52
Subthalamus4.46 ± 0.1
Temporal Lobe4.67 ± 0.41
Thalamus4.42 ± 0.4
White Matter4.21 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rtn4ip1CBCerebellum4.88
6.24
Rtn4ip1CTXCerebral cortex5.27
4.19
Rtn4ip1HIPHippocampal region4.41
3.89
Rtn4ip1HPFHippocampal formation3.25
2.8
Rtn4ip1HYHypothalamus0.57
0.52
Rtn4ip1LSXLateral septal complex0.46
0.25
Rtn4ip1MBMidbrain1.77
2.46
Rtn4ip1MYMedulla2.79
3.64
Rtn4ip1OLFOlfactory bulb4.23
4.18
Rtn4ip1PPons2.56
3.69
Rtn4ip1PALPallidum0.71
0.69
Rtn4ip1RHPRetrohippocampal region1.58
1.46
Rtn4ip1sAMYStriatum-like amygdalar nuclei0.18
0.12
Rtn4ip1STRStriatum0.76
0.64
Rtn4ip1STRdStriatum dorsal region0.53
0.53
Rtn4ip1STRvStriatum ventral region1.77
1.2
Rtn4ip1THThalamus1.59
1.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00405165 14 78 91 VHAASVNPIDVNMR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018