AutismKB 2.0

Annotation Detail for LRCH3


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Basic Information Top
Gene Symbol:LRCH3 ( FLJ20994,FLJ43245,FLJ44976,MGC4126 )
Gene Full Name: leucine-rich repeats and calponin homology (CH) domain containing 3
Band: 3q29
Quick LinksEntrez ID:84859; OMIM: NA; Uniprot ID:LRCH3_HUMAN; ENSEMBL ID: ENSG00000186001; HGNC ID: 28637
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus42 / 56401274
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult85 / 193912143
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma5 / 10688346
head and neck tumor14 / 136302102
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal176 / 336030752
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal12 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow2 / 4880140
brain52 / 110098947
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye9 / 21105442
heart4 / 8962644
intestine5 / 23447221
kidney10 / 21177747
larynx5 / 24145207
liver1 / 2077434
lung12 / 33697435
lymph1 / 4427022
lymph node20 / 91610218
mammary gland7 / 15327145
mouth7 / 67052104
muscle9 / 10771583
nerve0 / 157680 
ovary6 / 10205158
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate2 / 18934510
salivary gland0 / 201550 
skin5 / 21057423
spleen4 / 5395274
stomach4 / 9661941
testis21 / 33044263
thymus4 / 8113149
thyroid4 / 4747384
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular3 / 5178057
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1094_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.29 ± 0.28
Basal Forebrain5.37 ± 0.32
Basal Part of Pons5.4 ± 0.39
Cerebellar Cortex5.74 ± 0.21
Cerebellar Nuclei5.72 ± 0.43
Claustrum5.57 ± 0.6
Epithalamus5.36 ± 0.44
Frontal Lobe5.18 ± 0.43
Globus Pallidus5.71 ± 0.48
Hypothalamus5.1 ± 0.53
Insula5.24 ± 0.29
Limbic Lobe5.3 ± 0.48
Mesencephalon5.39 ± 0.38
Myelencephalon5.37 ± 0.48
Occipital Lobe5.48 ± 0.4
Parietal Lobe5.34 ± 0.44
Pontine Tegmentum5.32 ± 0.51
Striatum5.39 ± 0.47
Subthalamus5.28 ± 0.32
Temporal Lobe5.31 ± 0.36
Thalamus5.4 ± 0.32
White Matter6.68 ± 0.15
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00068275 26 625 650 GHASPLPPSAAPTTDSTDSITGQNSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018