AutismKB 2.0

Annotation Detail for TMEM25


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMEM25 ( FLJ14399 )
Gene Full Name: transmembrane protein 25
Band: 11q23.3
Quick LinksEntrez ID:84866; OMIM: NA; Uniprot ID:TMM25_HUMAN; ENSEMBL ID: ENSG00000149582; HGNC ID: 25890
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus48 / 56401285
neonate1 / 3109732
infant1 / 2362042
juvenile7 / 55556125
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor36 / 263845136
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor9 / 68959130
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal366 / 3360307108
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland9 / 33197271
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain266 / 1100989241
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye9 / 21105442
heart5 / 8962655
intestine7 / 23447229
kidney28 / 211777132
larynx0 / 241450 
liver3 / 20774314
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland12 / 15327178
mouth5 / 6705274
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate15 / 18934579
salivary gland0 / 201550 
skin1 / 2105744
spleen7 / 53952129
stomach13 / 96619134
testis15 / 33044245
thymus13 / 81131160
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus17 / 23287872
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P203115
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.1 ± 0.29
Basal Forebrain9.95 ± 0.17
Basal Part of Pons10.36 ± 0.16
Cerebellar Cortex10.24 ± 0.13
Cerebellar Nuclei9.84 ± 0.31
Claustrum9.99 ± 0.32
Epithalamus9.29 ± 0.41
Frontal Lobe10.03 ± 0.32
Globus Pallidus8.84 ± 0.3
Hypothalamus10.16 ± 0.42
Insula10.03 ± 0.14
Limbic Lobe9.79 ± 0.46
Mesencephalon9.81 ± 0.38
Myelencephalon9.92 ± 0.45
Occipital Lobe9.96 ± 0.34
Parietal Lobe10.03 ± 0.42
Pontine Tegmentum9.89 ± 0.38
Striatum9.75 ± 0.41
Subthalamus10.01 ± 0.28
Temporal Lobe10.04 ± 0.29
Thalamus9.97 ± 0.26
White Matter8.43 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem25CBCerebellum62.01
93.87
Tmem25CTXCerebral cortex79.9
68.95
Tmem25HIPHippocampal region42.84
66.19
Tmem25HPFHippocampal formation58.69
68.56
Tmem25HYHypothalamus53.91
45.49
Tmem25LSXLateral septal complex45.03
30.96
Tmem25MBMidbrain75.39
77.61
Tmem25MYMedulla87.35
100
Tmem25OLFOlfactory bulb61.15
53.86
Tmem25PPons74.03
92.67
Tmem25PALPallidum49.85
48.25
Tmem25RHPRetrohippocampal region82.93
73.15
Tmem25sAMYStriatum-like amygdalar nuclei46.86
37.78
Tmem25STRStriatum21.74
17.77
Tmem25STRdStriatum dorsal region13.96
11.88
Tmem25STRvStriatum ventral region26.15
21.26
Tmem25THThalamus78.35
82.62
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018