AutismKB 2.0

Annotation Detail for HAVCR2


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Basic Information Top
Gene Symbol:HAVCR2 ( FLJ14428,KIM-3,TIM3,TIMD3,Tim-3 )
Gene Full Name: hepatitis A virus cellular receptor 2
Band: 5q33.3
Quick LinksEntrez ID:84868; OMIM: 606652; Uniprot ID:TIMD3_HUMAN; ENSEMBL ID: ENSG00000135077; HGNC ID: 18437
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate15 / 31097482
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia13 / 97250133
normal92 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood25 / 123478202
bone0 / 716550 
bone marrow2 / 4880140
brain19 / 110098917
cervix0 / 481710 
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine2 / 2344728
kidney12 / 21177756
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen7 / 53952129
stomach0 / 966190 
testis0 / 3304420 
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P923370
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.19 ± 0.96
Basal Forebrain4.53 ± 0.59
Basal Part of Pons4.89 ± 0.39
Cerebellar Cortex3.86 ± 0.45
Cerebellar Nuclei5.3 ± 0.59
Claustrum4.26 ± 0.81
Epithalamus5.11 ± 0.6
Frontal Lobe4.25 ± 0.66
Globus Pallidus6.23 ± 0.31
Hypothalamus4.37 ± 1.19
Insula4.56 ± 0.57
Limbic Lobe4.33 ± 0.73
Mesencephalon4.41 ± 0.74
Myelencephalon4.43 ± 0.77
Occipital Lobe3.93 ± 0.68
Parietal Lobe4.34 ± 0.63
Pontine Tegmentum4.14 ± 0.79
Striatum4.84 ± 0.51
Subthalamus4.58 ± 0.16
Temporal Lobe4.42 ± 0.65
Thalamus4.43 ± 0.56
White Matter6.48 ± 0.57
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00803840 8 82 89 YWLNGDFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018