AutismKB 2.0

Annotation Detail for ZBTB45


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Basic Information Top
Gene Symbol:ZBTB45 ( DKFZp547H249,FLJ14486,ZNF499 )
Gene Full Name: zinc finger and BTB domain containing 45
Band: 19q13.43
Quick LinksEntrez ID:84878; OMIM: NA; Uniprot ID:ZBT45_HUMAN; ENSEMBL ID: ENSG00000119574; HGNC ID: 23715
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor21 / 119369175
germ cell tumor10 / 26384537
glioma12 / 106883112
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow1 / 4880120
brain40 / 110098936
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph1 / 4427022
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate9 / 18934547
salivary gland0 / 201550 
skin13 / 21057461
spleen4 / 5395274
stomach51 / 96619527
testis6 / 33044218
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1934_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.76 ± 0.37
Basal Forebrain5.72 ± 0.31
Basal Part of Pons6.04 ± 0.35
Cerebellar Cortex5.52 ± 0.46
Cerebellar Nuclei5.72 ± 0.44
Claustrum6.25 ± 0.58
Epithalamus5.4 ± 0.29
Frontal Lobe5.69 ± 0.43
Globus Pallidus5.74 ± 0.5
Hypothalamus5.21 ± 0.35
Insula5.56 ± 0.38
Limbic Lobe5.91 ± 0.41
Mesencephalon5.65 ± 0.38
Myelencephalon5.76 ± 0.41
Occipital Lobe5.69 ± 0.41
Parietal Lobe5.8 ± 0.43
Pontine Tegmentum5.55 ± 0.48
Striatum5.62 ± 0.5
Subthalamus5.86 ± 0.71
Temporal Lobe5.71 ± 0.33
Thalamus5.74 ± 0.42
White Matter5.57 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ZBTB45CBCerebellum48.24
77.71
ZBTB45CTXCerebral cortex100
100
ZBTB45HIPHippocampal region48.91
71.4
ZBTB45HPFHippocampal formation52.25
62.23
ZBTB45HYHypothalamus28.07
25.13
ZBTB45LSXLateral septal complex18.21
14.26
ZBTB45MBMidbrain32.2
30.51
ZBTB45MYMedulla43.39
50.02
ZBTB45OLFOlfactory bulb70.77
70.22
ZBTB45PPons32.85
35.92
ZBTB45PALPallidum40.12
40.77
ZBTB45RHPRetrohippocampal region59.39
51.49
ZBTB45sAMYStriatum-like amygdalar nuclei49.77
38.18
ZBTB45STRStriatum48.87
40.24
ZBTB45STRdStriatum dorsal region47.03
38.08
ZBTB45STRvStriatum ventral region60.74
51.23
ZBTB45THThalamus51.31
50.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018