AutismKB 2.0

Annotation Detail for ATAD1


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Basic Information Top
Gene Symbol:ATAD1 ( AFDC1,FLJ14600 )
Gene Full Name: ATPase family, AAA domain containing 1
Band: 10q23.31
Quick LinksEntrez ID:84896; OMIM: NA; Uniprot ID:ATAD1_HUMAN; ENSEMBL ID: ENSG00000138138; HGNC ID: 25903
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal210 / 336030762
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites1 / 4001524
bladder2 / 2975767
blood2 / 12347816
bone6 / 7165583
bone marrow0 / 488010 
brain57 / 110098951
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye10 / 21105447
heart6 / 8962666
intestine9 / 23447238
kidney11 / 21177751
larynx1 / 2414541
liver14 / 20774367
lung9 / 33697426
lymph1 / 4427022
lymph node12 / 91610130
mammary gland7 / 15327145
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas3 / 21481213
parathyroid3 / 20539146
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta14 / 28082549
prostate16 / 18934584
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach3 / 9661931
testis13 / 33044239
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P329777
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.02 ± 0.2
Basal Forebrain8.01 ± 0.09
Basal Part of Pons8.15 ± 0.19
Cerebellar Cortex8 ± 0.25
Cerebellar Nuclei8.18 ± 0.28
Claustrum8.09 ± 0.35
Epithalamus7.83 ± 0.15
Frontal Lobe7.9 ± 0.24
Globus Pallidus8.2 ± 0.2
Hypothalamus7.98 ± 0.24
Insula7.82 ± 0.35
Limbic Lobe8.1 ± 0.26
Mesencephalon8.06 ± 0.33
Myelencephalon7.96 ± 0.25
Occipital Lobe8.24 ± 0.28
Parietal Lobe8.04 ± 0.21
Pontine Tegmentum7.99 ± 0.23
Striatum8.09 ± 0.26
Subthalamus7.86 ± 0.24
Temporal Lobe7.92 ± 0.21
Thalamus7.95 ± 0.23
White Matter7.8 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atad1CBCerebellum20.47
46.06
Atad1CTXCerebral cortex100
100
Atad1HIPHippocampal region74.19
100
Atad1HPFHippocampal formation87.69
100
Atad1HYHypothalamus43.01
46.51
Atad1LSXLateral septal complex48.35
47.42
Atad1MBMidbrain24.08
33.93
Atad1MYMedulla15
27.6
Atad1OLFOlfactory bulb56.83
65.44
Atad1PPons21.38
37.54
Atad1PALPallidum43.33
54.68
Atad1RHPRetrohippocampal region100
100
Atad1sAMYStriatum-like amygdalar nuclei40.88
39.74
Atad1STRStriatum39.12
36.83
Atad1STRdStriatum dorsal region39.16
36.37
Atad1STRvStriatum ventral region34.37
34.33
Atad1THThalamus46.16
56.18
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ATAD1_HUMAN_39 7 39 45 DAIDPTR PRIDE
PAp00002305 26 313 338 EYVNSTSEESHDEDEIRPVQQQDLHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018