AutismKB 2.0

Annotation Detail for PLXDC2


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Basic Information Top
Gene Symbol:PLXDC2 ( FLJ14623,TEM7R )
Gene Full Name: plexin domain containing 2
Band: 10p12.31
Quick LinksEntrez ID:84898; OMIM: 606827; Uniprot ID:PXDC2_HUMAN; ENSEMBL ID: ENSG00000120594; HGNC ID: 21013
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus9 / 56401215
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal46 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone5 / 7165569
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart4 / 8962644
intestine1 / 2344724
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve3 / 15768190
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P161424
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.53 ± 0.37
Basal Forebrain7.8 ± 0.44
Basal Part of Pons8.07 ± 0.28
Cerebellar Cortex7.44 ± 0.21
Cerebellar Nuclei7.64 ± 0.16
Claustrum7.85 ± 0.41
Epithalamus8.34 ± 0.33
Frontal Lobe7.66 ± 0.4
Globus Pallidus8.73 ± 0.3
Hypothalamus7.82 ± 0.28
Insula7.91 ± 0.46
Limbic Lobe7.88 ± 0.45
Mesencephalon7.78 ± 0.44
Myelencephalon7.76 ± 0.43
Occipital Lobe7.83 ± 0.34
Parietal Lobe7.52 ± 0.35
Pontine Tegmentum7.59 ± 0.32
Striatum7.98 ± 0.38
Subthalamus8.21 ± 0.24
Temporal Lobe7.72 ± 0.38
Thalamus8 ± 0.43
White Matter8.47 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plxdc2CBCerebellum23.36
42.02
Plxdc2CTXCerebral cortex16.56
12.31
Plxdc2HIPHippocampal region13.55
13.93
Plxdc2HPFHippocampal formation22.43
22.53
Plxdc2HYHypothalamus16.93
14.27
Plxdc2LSXLateral septal complex22.63
18.31
Plxdc2MBMidbrain15.67
14.04
Plxdc2MYMedulla12.83
13.07
Plxdc2OLFOlfactory bulb22.65
18.07
Plxdc2PPons11.29
10.99
Plxdc2PALPallidum12.59
10.73
Plxdc2RHPRetrohippocampal region35.12
32.16
Plxdc2sAMYStriatum-like amygdalar nuclei17.92
14.08
Plxdc2STRStriatum9.34
6.87
Plxdc2STRdStriatum dorsal region7.24
5.15
Plxdc2STRvStriatum ventral region7.05
4.72
Plxdc2THThalamus23.52
20.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00045344 29 91 119 SFTDLLLDDGQDNNTQIEEDTDHNYYISR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018