AutismKB 2.0

Annotation Detail for RGS5


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Basic Information Top
Gene Symbol:RGS5 ( MST092,MST106,MST129,MSTP032,MSTP092,MSTP106,MSTP129 )
Gene Full Name: regulator of G-protein signaling 5
Band: 1q23.3
Quick LinksEntrez ID:8490; OMIM: 603276; Uniprot ID:RGS5_HUMAN; ENSEMBL ID: ENSG00000143248; HGNC ID: 10001
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst2 / 6231932
fetus69 / 564012122
neonate9 / 31097289
infant2 / 2362084
juvenile28 / 55556503
adult311 / 1939121160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor29 / 127942266
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor12 / 114246105
esophageal tumor1 / 1729057
gastrointestinal tumor32 / 119369268
germ cell tumor40 / 263845151
glioma7 / 10688365
head and neck tumor7 / 13630251
kidney tumor9 / 68959130
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia20 / 97250205
normal798 / 3360307237
ovarian tumor3 / 7668239
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS144 / 1256801145
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor40 / 125191319
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland45 / 331971355
ascites0 / 400150 
bladder2 / 2975767
blood2 / 12347816
bone5 / 7165569
bone marrow0 / 488010 
brain161 / 1100989146
cervix4 / 4817183
connective tissue13 / 14925587
ear12 / 16212740
embryonic tissue23 / 215722106
esophagus1 / 2020949
eye35 / 211054165
heart50 / 89626557
intestine49 / 234472208
kidney35 / 211777165
larynx2 / 2414582
liver5 / 20774324
lung41 / 336974121
lymph0 / 442700 
lymph node2 / 9161021
mammary gland10 / 15327165
mouth1 / 6705214
muscle20 / 107715185
nerve11 / 15768697
ovary3 / 10205129
pancreas77 / 214812358
parathyroid11 / 20539535
pharynx18 / 41328435
pituitary gland6 / 16585361
placenta16 / 28082556
prostate21 / 189345110
salivary gland0 / 201550 
skin9 / 21057442
spleen3 / 5395255
stomach56 / 96619579
testis57 / 330442172
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord6 / 13680438
uterus64 / 232878274
vascular219 / 517804229
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209070_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte4.2
AdrenalCortex7.8
Adrenalgland35.6
Amygdala14.15
Appendix23.75
AtrioventricularNode3.25
BDCA4+_DentriticCells4.2
Bonemarrow4.25
BronchialEpithelialCells4.15
CD105+_Endothelial4.05
CD14+_Monocytes3.95
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid4.8
CD34+5.1
CD4+_Tcells4.35
CD56+_NKCells4.55
CD71+_EarlyErythroid4
CD8+_Tcells3.65
CardiacMyocytes40.25
Caudatenucleus4.4
Cerebellum3.55
CerebellumPeduncles5
CiliaryGanglion3.25
CingulateCortex11.3
Colorectaladenocarcinoma3.85
DorsalRootGanglion3.3
FetalThyroid24.55
Fetalbrain4.2
Fetalliver3.75
Fetallung5.2
GlobusPallidus4.1
Heart5.6
Hypothalamus6.7
Kidney4
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)3.35
Liver5.85
Lung4.65
Lymphnode8.65
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)5.95
MedullaOblongata17.65
OccipitalLobe33.6
OlfactoryBulb7.85
Ovary2.85
Pancreas3.45
PancreaticIslet5.1
ParietalLobe7.05
Pituitary23.45
Placenta4.2
Pons15.75
PrefrontalCortex15.05
Prostate6.8
Salivarygland3.7
SkeletalMuscle7.5
Skin3.3
SmoothMuscle4.8
Spinalcord4.75
SubthalamicNucleus11
SuperiorCervicalGanglion16.25
TemporalLobe7.5
Testis3.85
TestisGermCell17.55
TestisIntersitial6.7
TestisLeydigCell6.9
TestisSeminiferousTubule5.3
Thalamus5.25
Thymus3.35
Thyroid26.05
Tongue6.3
Tonsil4.7
Trachea8.5
TrigeminalGanglion4.55
Uterus28
UterusCorpus5.15
WholeBlood4.4
Wholebrain4.4
colon5.55
pineal_day5.58
pineal_night5.86
retina7.375
small_intestine33.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P51518
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.87 ± 0.4
Basal Forebrain7.22 ± 0.3
Basal Part of Pons7.61 ± 0.57
Cerebellar Cortex6.63 ± 0.39
Cerebellar Nuclei8.21 ± 0.2
Claustrum6.96 ± 0.72
Epithalamus6.62 ± 0.88
Frontal Lobe7.3 ± 0.5
Globus Pallidus8.32 ± 0.42
Hypothalamus7.02 ± 0.69
Insula7.13 ± 0.61
Limbic Lobe7.05 ± 0.55
Mesencephalon7.39 ± 0.63
Myelencephalon7.29 ± 0.6
Occipital Lobe7.04 ± 0.56
Parietal Lobe7.36 ± 0.58
Pontine Tegmentum7.35 ± 0.6
Striatum8.06 ± 0.61
Subthalamus7.54 ± 0.63
Temporal Lobe7.15 ± 0.4
Thalamus7.55 ± 0.46
White Matter6.91 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rgs5CBCerebellum27.58
38.25
Rgs5CTXCerebral cortex16.05
14.54
Rgs5HIPHippocampal region15.25
19.04
Rgs5HPFHippocampal formation14.91
16.46
Rgs5HYHypothalamus15
14.94
Rgs5LSXLateral septal complex15.54
15.34
Rgs5MBMidbrain17.8
18.82
Rgs5MYMedulla22.44
24.19
Rgs5OLFOlfactory bulb19.81
17.32
Rgs5PPons21.61
21.98
Rgs5PALPallidum13.77
13.63
Rgs5RHPRetrohippocampal region14.51
13.02
Rgs5sAMYStriatum-like amygdalar nuclei11.65
11.53
Rgs5STRStriatum14.59
13.58
Rgs5STRdStriatum dorsal region15.04
14.39
Rgs5STRvStriatum ventral region14.16
11.35
Rgs5THThalamus17.73
17.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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